Abstract
Osteonecrosis of the jaw in the patients receiving bisphosphonate or denosumab treatment is a serious condition. Despite several terminologies have been used for this condition, bisphosphonate-related osteonecrosis of the jaw (BRONJ) and medication-related osteonecrosis of the jaw (MRONJ) are applied throughout this chapter. BRONJ/MRONJ clinically presents as exposed bone of the mandible or the maxilla with further symptoms such as pain, drainage, or swelling. Histopathological confirmation is strongly recommended to prove the clinical diagnosis whenever surgical intervention is performed. This chapter describes the macroscopic and microscopic features of BRONJ/MRONJ and discusses the histopathologic differential diagnosis of this condition.
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Chaisuparat, R., Jham, B.C. (2015). Histopathology of Medication-Related Osteonecrosis of the Jaw. In: Otto, S. (eds) Medication-Related Osteonecrosis of the Jaws. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43733-9_12
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DOI: https://doi.org/10.1007/978-3-662-43733-9_12
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