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Retinoblastoma: Metastatic Disease

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Clinical Ophthalmic Oncology

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Abstract

Patients with extraocular retinoblastoma have historically had a poor prognosis, but recently significant improvements in survival have been reported. In this chapter, we will review data indicating that the majority of patients with regional extraocular disease can be successfully treated with conventional chemotherapy and external beam radiation therapy and that patients with distant metastatic disease appear to benefit from the addition of high-dose chemotherapy with stem cell rescue.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, 185, New York, NY, 10065, USA

    Ira J. Dunkel MD

  2. Hemato-Oncology Department, Hospital JP Garrahan, Combate de los Pozos 1881 (C1245AAL), Buenos Aires, Argentina

    Guillermo L. Chantada MD

Authors
  1. Ira J. Dunkel MD
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  2. Guillermo L. Chantada MD
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Corresponding author

Correspondence to Ira J. Dunkel MD .

Editor information

Editors and Affiliations

  1. Dept. of Ophthalmic Oncology, Cole Eye Institute Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Arun D. Singh

  2. Department of Ophthalmology, Children's Hospital Los Angeles, Los Angeles, USA

    A. Linn Murphree

  3. University of California, San Francisco, California, USA

    Bertil E. Damato

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© 2015 Springer-Verlag Berlin Heidelberg

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Dunkel, I.J., Chantada, G.L. (2015). Retinoblastoma: Metastatic Disease. In: Singh, A., Murphree, A., Damato, B. (eds) Clinical Ophthalmic Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43451-2_18

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  • DOI: https://doi.org/10.1007/978-3-662-43451-2_18

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-43450-5

  • Online ISBN: 978-3-662-43451-2

  • eBook Packages: MedicineMedicine (R0)

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