Eye Pathology pp 197-232 | Cite as

Glaucoma

  • Claudia Auw-Haedrich
  • Peter Meyer
  • Rita Van Ginderdeuren
Chapter

Abstract

Glaucoma or a too high intraocular pressure causes damage of the optic nerve and diminished vision. Glaucoma occurs in most cases due to reduction of the aqueous humour outflow via the trabecular meshwork. Various aetiologies are known and were illustrated as subtopics in the following chapter. Primary open-angle glaucoma is the most often diagnosed glaucoma type which shows microscopical changes of the trabecular meshwork especially the uveal part while macroscopically the angle seems to be open, hence the name. There are secondary open-angle glaucomas with materials like pigment or pseudoexfoliation material blocking the aqueous outflow. Pretrabecular hindrances like scars following inflammation, bleeding, angle trauma, neovascularisation or congenital anomalies have the same effect with resulting increased ocular pressure and optic nerve damage. A second large group of glaucoma is the closed-angle glaucoma which can be due to anatomical reasons or secondary blockage of the aqueous flow from the posterior to the anterior chamber and secondary narrowing of the anterior chamber angle.

Keywords

Ischemia Glutathione Adenosine Retina Dexamethasone 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Claudia Auw-Haedrich
    • 1
  • Peter Meyer
    • 2
  • Rita Van Ginderdeuren
    • 3
  1. 1.Histology Lab, Eye CenterUniversity FreiburgFreiburgGermany
  2. 2.Division of Histology LabAugenspital BaselBaselSwitzerland
  3. 3.Department of Ophthalmology and PathologyUZ LeuvenLeuvenBelgium

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