Etiology of Burkitt’s Lymphoma
Is the Epstein-Barr virus (EBV) oncogenic? As discussed elsewhere (de-Thé et al., 1972b) the EBV appears to have oncogenic potential in vitro when uninfected lymphocytes are used as target cells.
Is the EBV a necessary factor for the development of BL? To answer that critical question, we are implementing a large prospective sero-epidemiological study in Uganda, East Africa. Our aim is to distinguish between three hypotheses regarding the relationship between EBV and BL.
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