Abstract

The possible role of natural and synthetic chemical carcinogens in the aetiology of human liver cancer has been reviewed recently by Magee (1971). The synthetic chemical carcinogens generally have little relation to the situation in man and remain laboratory shelf carcinogens with the interesting exception of the nitrosamines. The possibilities among the natural carcinogens, however, appears more promising and the pyrrolizidine alkaloids from Senecio and Crotalaria plants, the glycosides from the cycads, the toxic agents from rice contaminated by Penicillium islandicum, and the aflatoxins from the Aspergillus moulds have been the subject of much endeavour during the last decade.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alpert, M. E., Davidson, C. S., Wogan, G. N.: Gastroenterology 54, 49 (1968).Google Scholar
  2. Bourgeosis, C. H., Keschamras, N., Comer, D. S., Harikul, S., Evans, H., Olson, L., Smith, T., Beek, M. R.: J. med. Ass. Thailand 52, 553 (1969).Google Scholar
  3. Bourgeois, C. H., Shank, R. C., Grossmann, R. A., Johnson, D. O., Wooding, W. L., Chandavimol, P.: Lab. Invest. 24, 206 (1971).PubMedGoogle Scholar
  4. Carnaghan, R. B. A.: Brit. J. Cancer 21, 811 (1967).PubMedCrossRefGoogle Scholar
  5. Coady, A.: Ethiopian M. J. 3, 173 (1965).Google Scholar
  6. Depaola, D., Strano, A. J., Horn, H. C.: Int. Path. 9, 43 (1968).Google Scholar
  7. Derecondo, A. M., Frayssinet, C., Lafarge, C., LE Breton, E.: Biochim. biophys. Acta. (Amst.) 119, 322 (1966).CrossRefGoogle Scholar
  8. Lebreton, E., Frayssinet, C., Boy, J.: C. R. Acad. Sci. (Paris) 255, 784 (1962).Google Scholar
  9. Magee, P. N.: I.A.R.C. Publication 1, 110 (1971).Google Scholar
  10. Oettle, A. G.: S. Afr. med. J. 39, 817 (1965).PubMedGoogle Scholar
  11. Olson, L. C., Bourgeois, C., Cotton, R., Harikul, S., Grossmann, R., Smith, T.: Amer. J. Dis. Child. 120, 1 (1970).PubMedGoogle Scholar
  12. Purchase, I. F. H., VanDerWatt, J. J.: Fd. Cosmet. Toxicol. 6, 555 (1968).CrossRefGoogle Scholar
  13. Sercxhanssen, A.: Arch. Environm. Hlth. 20, 729 (1970).CrossRefGoogle Scholar
  14. Svoboda, D., Grady, H., Higginson, J.: Amer. J. Path. 49, 6 (1966).Google Scholar
  15. Torres, F. O., Purchase, I. F. H., VanDerWatt, J. J.: J. Path. 102, 163 (1970).PubMedCrossRefGoogle Scholar
  16. Wogan, G. N.: Bact. Rev. 30, 460 (1966).PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1972

Authors and Affiliations

  • C. A. Linsell
    • 1
  • F. G. Peers
    • 1
  1. 1.Nairobi Regional Centre International Agency for Research on CancerNairobiKenya

Personalised recommendations