B-Cell Reconstitution After Allogeneic Bone Marrow Transplantation (ABMT)

  • M. Gobbi
  • F. Lauria
  • P. Tazzari
  • D. Raspadori
  • R. Conte
  • G. Bandini
  • A. Guarini
  • P. Paolucci
  • S. Tura
Part of the Experimental Hematology book series (HEMATOLOGY)

Abstract

It is well known that patients subjected to ABMT present a profound and long lasting immunological impairment. Although the pattern of the phenotypic expression and the function of T cells, as well as the immunoglobulin levels and the capacity to produce specific humoral responce after ABMT have been extensively studied (1), few informations have been produced on the B-cell lineage. In this study we analized the pattern of B-cell reconstitution in the bone marrow (BM) and peripheral blood (PB) in the firtst 3 months after ABMT.

Keywords

Myeloma Prednisone Allo 

References

  1. 1).
    R.P. Witherspoon, L.G. Lum, R. Storb: Immunologic reconstitution after human marrow grafting. Semin. Hematol. 21, 2–10, 1984.PubMedGoogle Scholar
  2. 2).
    M. Gobbi, F. Caligaris-Cappio, G. Janossy: Normal equivalent cells of B cell malignancies: analysis with monoclonal antibodies. Br. J. Haematol 54, 393–403, 1983.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • M. Gobbi
    • 1
  • F. Lauria
    • 1
  • P. Tazzari
    • 1
  • D. Raspadori
    • 1
  • R. Conte
    • 2
  • G. Bandini
    • 1
  • A. Guarini
    • 1
  • P. Paolucci
    • 3
  • S. Tura
    • 1
  1. 1.Istituto di Ematologia “L. e A. Seragnoli”Italy
  2. 2.Centro TrasfusionaleItaly
  3. 3.Clinica Pediatrica Policlinico S. OrsolaBolognaItaly

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