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B-Cell Reconstitution After Allogeneic Bone Marrow Transplantation (ABMT)

  • M. Gobbi
  • F. Lauria
  • P. Tazzari
  • D. Raspadori
  • R. Conte
  • G. Bandini
  • A. Guarini
  • P. Paolucci
  • S. Tura
Part of the Experimental Hematology book series (HEMATOLOGY)

Abstract

It is well known that patients subjected to ABMT present a profound and long lasting immunological impairment. Although the pattern of the phenotypic expression and the function of T cells, as well as the immunoglobulin levels and the capacity to produce specific humoral responce after ABMT have been extensively studied (1), few informations have been produced on the B-cell lineage. In this study we analized the pattern of B-cell reconstitution in the bone marrow (BM) and peripheral blood (PB) in the firtst 3 months after ABMT.

Keywords

Bone Marrow Multiple Myeloma Bone Marrow Transplantation Serum Immunoglobulin Immunoglobulin Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1).
    R.P. Witherspoon, L.G. Lum, R. Storb: Immunologic reconstitution after human marrow grafting. Semin. Hematol. 21, 2–10, 1984.PubMedGoogle Scholar
  2. 2).
    M. Gobbi, F. Caligaris-Cappio, G. Janossy: Normal equivalent cells of B cell malignancies: analysis with monoclonal antibodies. Br. J. Haematol 54, 393–403, 1983.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • M. Gobbi
    • 1
  • F. Lauria
    • 1
  • P. Tazzari
    • 1
  • D. Raspadori
    • 1
  • R. Conte
    • 2
  • G. Bandini
    • 1
  • A. Guarini
    • 1
  • P. Paolucci
    • 3
  • S. Tura
    • 1
  1. 1.Istituto di Ematologia “L. e A. Seragnoli”Italy
  2. 2.Centro TrasfusionaleItaly
  3. 3.Clinica Pediatrica Policlinico S. OrsolaBolognaItaly

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