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Pulmonary Follow-Up in Patients with Bone Marrow Transplantation (BMT) and Graft-Versus-Host Disease (GVHD)

  • R. Rodriguez-Roisin
  • J. Roca
  • P. Marín
  • A. Grañena
  • A. Agustí-Vidal
  • C. Rozman
Part of the Experimental Hematology book series (HEMATOLOGY)

Abstract

Pulmonary complications have emerged as one of the major problem of allogeneic bone marrow transplantation (ITT). Interstitial pneumonitis is the most well-]mown complication; however, there is also increasing evidence to support the view that obstructive lung disease can be present in BMT recipients (Rodriguez-Roisín et al, 1984; Ralph et al, 1984; Wyatt et al, 1984). We report here the main pulmonary clinical and functional findings observed in 25 consecutive patients submitted to BMT during an 18 month-period, 20 of whom associated some form of acute and/or chronic graft-versus-host disease (GVHD)

Keywords

Bone Marrow Transplantation Aplastic Anemia Acute Leukemia Obliterative Bronchiolitis Bone Marrow Transplantation Recipient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Ralph DD, Springneyer SC, Sullivan KM, Hackman RC, Storb R, Thomas ED (1984). Rapidly progressive air-flow obstruction in marrow transplant recipients. Possible association between obliterative bronchiolitis and chronic graft-versus-host disease. Am Rev Respir Dis, 129: 641–44.Google Scholar
  2. Rodriguez-Roisín R, Roca J, Cïranena A, Agusti-Vidal A, Rozman C (1984). Obliterative bronchiolitis: a distinct pathophysiologicai form of pulmonary involvement in bone marrow transplantation. Exp Hematol, 12 (Suppl 15): 12–14.Google Scholar
  3. Wyatt SE, Nunn P, Have JM, et al (1984). Airways obstruction associated with graft versus host disease after bone marrow transplantation. Thorax; 39: 887–894PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • R. Rodriguez-Roisin
    • 1
  • J. Roca
    • 1
  • P. Marín
    • 1
  • A. Grañena
    • 1
  • A. Agustí-Vidal
    • 1
  • C. Rozman
    • 1
  1. 1.Departament de Medicina (Servei de Pneumologia: Escola d’Hematologia “Farreras Valenti”), Hospital Clínic, Facultat de MedicinaUniversitat de BarcelonaBarcelonaSpain

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