Abstract
In 1906, a neuropsychiatrist by the name of Alois Alzheimer presented a paper to the Association of Southwest German Specialists in Mental Diseases on what would become a classic case. His paper, published the following year, described a disorder that would later be called Alzheimer’s disease. The following is an excerpt from the case description obtained during the patient’s psychiatric hospitalization (Alzheimer, 1907):
A woman 51 years of age exhibited ideas of jealousy against her husband as the first notable symptom. Soon a rapidly progressing loss of memory became apparent; she could no longer find her way around the home, dragged objects back and forth, hid them; at times she believed someone wanted to kill her and began to shout loudly. (p. 146)
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Alzheimer, A. (1907). Uber eine eigenartige Erkrankung der Hirnrinde. Allg. Z. Psychiatrie Psychisch-Gerichtlich. Med., 64, 146–148.
Ban, T. A. (1987). Pharmacologic perspectives in therapy of depression in the elderly. In: G. L. Maddox and E. W. Busse (Eds.), Aging: The universal experience (pp. 127–133 ). New York: Springer.
Barnes, D. M. (1987). Alzheimer protein is also in infant brains. Science, 238, 1652.
Bergener, M., and Hesse, C. (1987). Research on Alzheimer disease in German- speaking countries. Alzheimer Disease and Related Disorders, 1, 193–199.
Bondareff, W., Mountjoy, C. Q., Roth, M., Rossor, M. N., Iversen, L. L., Reynolds, G. P., and Hauser, D. L. (1987). Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease. Alzheimer Disease and Associated Disorders, 1, 256–262.
Butler, R. N. (1978). Alzheimer’s disease-senile dementia and related disorders: The role of NIA. In: R. Katzman, R. D. Terry, and K. L. Bick (Eds.), Alzheimer’s disease: Senile dementia and related disorders (pp. 5–9 ). New York: Raven Press.
Cain, S. T., and Nemeroff, C. B. (1987). Neuropeptides and neurotransmitters in Alzheimer’s disease. In: G. L. Maddox and E. W. Busse (Eds.), Aging: The universal experience (pp. 63–80 ). New York: Springer.
Cohen, D., and Eisdorfer, C. (1988). Depression in family members caring for a relative with Alzheimer’s disease. Journal of the American Geriatrics Society, 36, 885–889.
Cohen, G. D. (1988a). The brain in human aging. New York: Springer.
Cohen, G. D. (1988b). Disease models in aging: Brain and behavior considerations. In: J. E. Birren and V. L. Bengtson (Eds.), Emergent theories of aging (pp. 83–89 ).
Davis, K. L., Hollander, E., Davidson, M., Davis, B. M., Mohs, R. C., and Horvath, T. B. (1987). Induction of depression with oxotremorine in patients with Alzheimer’s disease. American Journal of Psychiatry, 144, 468–471.
Dysken, M. (1987). A review of recent clinical trials in the treatment of Alzheimer’s disease. Psychiatric Annals, 17, 178–191.
Fairburn, C. G., and Hope, R. A. (1988). Changes in eating in dementia. Neurobiology of Aging, 9, 28–29.
Gage, F. H., Chen, K. S., Buzsaki, G., and Armstrong, D. (1988). Experimental approaches to age-related cognitive impairments. Neurobiology of Aging, 9, 645–655.
Greenwald, B. S., Mathe, A. A., Mohs, R., Levy, M. I., Johns, C. A., and Davis, K. L. (1986). Cortisol and Alzheimer’s disease Dexamethasone suppression, dementia severity, and affective symptoms. American Journal of Psychiatry, 143, 442–446.
Group for the Advancement of Psychiatry. (1988). The psychiatric treatment of Alzheimer’s disease. New York: Bruner Mazel.
Haley, W. E., Levine, E. G., Brown, L., Berry, J. W., and Hughes, G. H. (1987). Psychological, social, and health consequences of caring for a relative with senile dementia. Journal of the American Geriatrics Society, 35, 405–411.
Jenike, M. A. (1985). Monoamine oxidase inhibitors as treatment for depressed patients with primary degenerative dementia (Alzheimer’s disease). American Journal of Psychiatry, 142, 763–764.
Jenike, M. A. (1988). Alzheimer’s disease-what the practicing clinician needs to know. Journal of Geriatric Psychiatry and Neurology, 1, 37–46.
Kiecolt-Glaser, J. K., Glaser, R., Dyer, C., Shuttleworth, E. C., Ogrocki, P., and Speicher, C. E. (1987). Chronic stress and immune function in family caregivers of Alzheimer disease victims. Psychosomatic Medicine, 49, 523–535.
Martin, M. B., Owen, C. M., and Morihisa, J. M. (1987). An overview of neurotransmitters and neuroreceptors. In: R. E. Hales and S. C. Yudofsky (Eds.), Testbook of neuropsychiatry (pp. 55–85 ). Washington DC: The American Psychiatric Press.
Merriam, A. E., Aronson, M. K., Gaston, P., Wey, S., and Katz, I. (1988). The psychiatric symptoms of Alzheimer’s disease. Journal of the American Geriatrics Society, 36, 1–6.
Morris, J. C., Rubin, E. H., Morris E. J., and Mandel, S. A. (1987). Senile dementia of the Alzheimer’s type: An important risk factor for serious falls. Journal of Gerontology, 42, 412–417.
Nemeroff, C. B. (1988). The neurobiology of aging and the neurobiology of depression: Is there a relationship? Neurobiology of Aging, 9, 120–122.
Patterson, J. F. (1988). A preliminary study of carbamazepine in the treatment of assaultive patients with dementia. Journal of Geriatric Psychiatry and Neurology, 1, 21–23.
Reifler, B. V., and Larson, E. L. (1988). Excess disability in demented elderly outpatients: The rule of the halves. Journal of the American Geriatrics Society, 36, 82–83.
Reifler, B. V., Larson, E., Terri, L., and Poulsen, M. (1986). Dementia of the Alzheimer’s type and depression. Journal of the American Geriatrics Society, 34, 855–859.
Reisberg, B., Ferris, S. H., deLeon, M. J., Crook, T., and Haynes, N. (1987). Senile dementia of the Alzheimer’s type. In: M. Bergener (Ed.), Psychogeriatrics: An international handbook (pp. 306–334 ). New York: Springer.
Rubin, E. H., Drevets, W. C., and Burke, W. J. (1988). The nature of psychotic symptoms in senile dementia of the Alzheimer’s type. Journal of Geriatric Psychiatry and Neurology, 1, 16–20.
Rubin, E. H., Morris, J. C., and Berg, L. (1988). The progression of personality change in senile dementia of the Alzheimer’s type. Journal of the American Geriatrics Society, 35, 721–725.
Salzman, C. (1986). Caution urged in using MAOIs with the elderly. American Journal of Psychiatry, 143, 118–119.
Stone, J. H. (1987). Alzheimer’s disease and related disorders association. In: G. L. Maddox (Ed.), The encyclopedia of aging (p. 30 ). New York: Springer.
Sunderland, T., Rubinow, D. R., Tariot, P. N., Cohen, R. M., Newhouse, P. A., Mellow, A. M., Mueller, E. A., and Murphy, D. L. (1987). CSF somatostatin in patients with Alzheimer’s disease, older depressed patients, and age-matched control subjects. American Journal of Psychiatry, 144, 1313–1316.
Swearer, J. M., Drachman, D. A., O’Donnell, B. F., and Mitchell, A. L. (1988). Troublesome and disruptive behaviors in dementia. Journal of the American Geriatrics Society, 36, 784–790.
Tariot, P. N., Cohen, R. M., Sunderland, T., Newhouse, P. A., Yount, D., Mellow, A. M., Weingartner, H., Mueller, E. A., and Murphy, D. L. (1987). L-Deprenyl in Alzheimer’s disease. Archives of General Psychiatry, 44, 427–433.
Tariot, P. N., Gross, M., Sunderland, T., Cohen, M. R., Weingartner, H., Murphy, D. L., and Cohen, R. M. (1988). High-dose naloxone in older normal subjects: Implications for Alzheimer’s disease. Journal of the American Geriatrics Society, 36, 681–686.
Teri, L., Larson, E., and Reifler, B. V. (1988). Behavioral disturbance in dementia of the Alzheimer’s type. Journal of the American Geriatrics Society, 36, 7–12.
U.S. Department of Health and Human Services. (1987). Differential diagnosis of dementing disorders. National Institute of Health Consensus Development Statement, 6, 1–27.
Veith, R. C., and Raskind, M. A. (1988). The neurobiology of aging: Does it predispose to depression? Neurobiology of Aging, 9, 101–117.
White, N., and Cunningham, W. R. (1988). Is terminal drop pervasive or specific? Journal of Gerontology, 43, 141–144.
Whitehouse, P. J. (1987). Neurotransmitter receptor alterations in Alzheimer’s disease: A review. Alzheimer Disease and Associated Disorders, 1, 9–18.
Whitehouse, P. J. (1988). Specific neurochemical systems and memory. Neurobiology of Aging, 9, 639–640.
Wolf-Klein, G. P., Silverstone, F. A., Brod, M. S., Levy, A., Foley, C. J., Termotto, V., and Breuer, J. (1988). Are Alzheimer patients healthier? Journal of the American Geriatrics Society, 36, 219–224.
Wolozin, B. L., Pruchnicki, A., Dickson, D. W., and Davies, P. (1986). A neuronal antigen in the brain of Alzheimer patients. Science, 232, 648–650.
Zubenko, G. S., Cohen, B. M., Reynolds, C., Boller, F., Malinakova, I., and Keefe, N. (1987). Platelet membrane fluidity in Alzheimer’s disease and major depression. American Journal of Psychiatry, 144, 860–868.
Zweig, R. M., Ross, C. A., Hedreen, J. C., Steele, C., Cardillo, J. E., Whitehouse, P. J., Folstein, M., and Price, D. L. (1988). The neuropathology of aminergic nuceli in Alzheimer’s disease. Alzheimer Disease and Associated Disorders, 2, 231.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer Science+Business Media New York
About this chapter
Cite this chapter
Cohen, G.D. (1990). Biopsychiatry in Alzheimer’s Disease. In: Lawton, M.P. (eds) Annual Review of Gerontology and Geriatrics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-40455-3_7
Download citation
DOI: https://doi.org/10.1007/978-3-662-40455-3_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-39398-7
Online ISBN: 978-3-662-40455-3
eBook Packages: Springer Book Archive