Abstract
General anaesthesia produced by inhalation anaesthetics and neurolept anaesthesia is associated with profound changes in renal function [1–3]. Renal blood flow, glomerular filtration rate, electrolyte and water excretion are all depressed (Tables 1 and 2). The mechanisms responsible for these changes include: decreases of cardiac output and arterial blood pressure, increased sympatho-adrenal activity, release of antidiuretic hormone (ADH), and possibly an aldosterone effect on the tubules secondary to the activation of the renin-angiotensin system. However, renal function is usually restored within a few hours after termination of anaesthesia and surgery, with the exception of free water excretion, which is often impaired for several days, probably due to remaining high ADH activity [4].
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© 1982 Springer-Verlag Berlin Heidelberg
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Järnberg, P.O. (1982). Effects of Inhalation Anaesthetics on Renal Function A Brief Review with Special Reference to Renal Handling of Fluoride Ions. In: Peter, K., Jesch, F. (eds) Inhalation Anaesthesia Today and Tomorrow. Anaesthesiology and Intensive Care Medicine / Anaesthesiologie und Intensivmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-39944-6_21
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DOI: https://doi.org/10.1007/978-3-662-39944-6_21
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