Skip to main content

Wirkungen von Amilorid und Triamteren auf die Lipolyse und den durch Enzyme induzierten Glucosetransport isolierter Fettzellen

  • Chapter
Naunyn Schmiedebergs Archiv für Pharmakologie

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 64.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Baba, W. I., and G. R. Tudhope: Site and mechanism of action of the diuretic, triamterene. Clin. Sci. 27, 181–193 (1964).

    CAS  PubMed  Google Scholar 

  • Baer, J. E., C. B. Jones, S. A. Spitzer, and H. F. Russo: The potassium-sparing and natriuretic acitivity of N-amidino-3, 5-diamino-6-chloropyrazin carboxamide hydroehloride dihydrate (Amiloride hydrochloride). J. Pharmacol. exp. Ther. 157, 472–485 (1967).

    CAS  PubMed  Google Scholar 

  • Ball, G. M., and J. A. Greene: Localization of the site of action of triamterene diuretic. Proc. Soc. exp. Biol. (N. Y.) 113, 326–328 (1963).

    Article  CAS  Google Scholar 

  • Blecher, M.: Phospholipase C and mechanisms of action of insulin and cortisol on glucose entry into free adipose cells. Biochem. biophys. Res. Commun. 21, 202–209 (1965).

    Article  CAS  PubMed  Google Scholar 

  • Blecher, M.: On the mechanism of action of phospholipase A and insulin on glucose entry into free adipose cells. Biochem. biophys. Res. Commun. 23, 68–74 (1966).

    Article  CAS  PubMed  Google Scholar 

  • — Effects of insulin and phospholipase A on glucose transport across the plasma membrane of free adipose cells. Biochim. biophys. Acta (Amst.) 137, 557–571 (1967 a).

    CAS  Google Scholar 

  • — Enzyme specifity in the stimulation of glucose transport in the free adipose cells by phospholipases. Biochim. biophys. Acta (Amst.) 137, 572–574 (1967b).

    CAS  Google Scholar 

  • — Evidence for the involvement of cyclic-3′, 5′-adenosine monophosphate in glucose utilization by isolated rat epididymal adipose cells. Biochem. biophys. Res. Commun. 27, 560–567 (1967).

    Article  CAS  PubMed  Google Scholar 

  • — N. S. Merlino, and J. T. Ro’ane: Control of the metabolism and lipolytic effects of cyelic-3′,5′-adenosine monophosphate in adipose tissue by insulin, methylxanthines, and nicotinic acid. J. biol. Chem. 243, 3973–3977 (1968).

    CAS  PubMed  Google Scholar 

  • Bray, C. A.: Inhibition of glucose oxidation in adipose tissue by dibutyryladenosine-3′, 5′-phosphate. Biochem. biophys. Res. Commun. 28, 621–627 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Bruchhausen, F. v.: Hemmung des α-Amino-isobuttersäure-Transportes in das isolierte Fettgewebe durch N6 · O2′-Dibutyryl-adenosin-3′ · 5′-phosphat. Hoppe-Seylers Z. physiol. Chem. 349, 1437–1439 (1968).

    Google Scholar 

  • —, u. H. K. Bartelheimer: Veränderungen von Elektrolytbewegungen durch Diuretica am isolierten Fettgewebe. Naunyn-Schmiedebergs Arch. Pharmak. exp. Path. 260, 97–98 (1968).

    Article  Google Scholar 

  • —, u. H. Herken: Wirkungen des 6-Aminonicotinsäureamids auf die insulinabhängige Glucoseaufnahme in das epididymale Fettgewebe. Naunyn-Schmiedebergs Arch. Pharmak. exp. Path. 254, 388–400 (1966).

    Article  Google Scholar 

  • — H. J. Voss u. H.-J. Merker: Wirkung von Triamteren auf insulinstimulierbare Prozesse des Fettgewebes. Naunyn-Schmiedebergs Arch. Pharmak. exp. Path. 256, 416–429 (1967).

    Article  Google Scholar 

  • — I. Kaiser u. H. Herken: Über Wirkungen von N-Amidino-3, 5-diamino-6-chloro-pyrazincarboxamid (Amilorid) auf den Glucosetransport und die Proteinsynthese des epididymalen Fettgewebes der Ratte. Naunyn-Schmiedebergs Arch. Pharmak. exp. Path. 262, 139–151 (1969).

    Article  Google Scholar 

  • Butcher, R. W., and C. E. Baird: Effects of lipolytic and antilipolytic substances on adenosine-3′5′-monophosphate levels in isolated fat cells. J. biol. Chem. 243, 1705–1712 (1968).

    CAS  PubMed  Google Scholar 

  • — J. G. T. Sneyd, C. R. Park, and E. W. Sutherland: Effect of insulin on adenosine 3′, 5′-monophosphate in the rat epididymal fat pad. J. biol. chem. 241, 1651–1653 (1966).

    CAS  PubMed  Google Scholar 

  • Crabbé, J.: A hypothesis concerning the mode of action of amiloride and of triamterene. Arch. int. Pharmacodyn. 173, 474–477 (1968).

    PubMed  Google Scholar 

  • Dreierkauf, F. A., and H. L. Boom: Changes in the phosphatide pattern of yeast cells in relation to active carbohydrate transport. Biochim. biophys. Acta (Amst.) 150, 214–225 (1968).

    Google Scholar 

  • Ehrlich, E. N., and J. Crabbé: The mechanism of action of amipramizide. Pflügers Arch. 302, 79–96 (1968).

    Article  CAS  PubMed  Google Scholar 

  • Eigler, J., J. Kelter u. E. Renner: Wirkungscharakteristika eines neuen Acylguanidins — Amiloride-HCl (MK 870) — an der isolierten Haut von Amphibien. Klin. Wschr. 45, 737–738 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Fain, J. N.: Adrenergic blockade of hormone-induced lipolysis in isolated fat cells. Ann. N. Y. Acad. Sci. 139, 879–890 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Fain, J. N., V. P. Kovacev, and R. O. Scow: Effect of growth hormone and dexamethasone on lipolysis and metabolism in isolated fat cells of the rat. J. biol. Chem. 240, 3522–3529 (1965).

    CAS  PubMed  Google Scholar 

  • Hanahan, D. J., and J. N. Olley: Chemical nature of monophosphoinositides. J. biol. Chem. 231, 813–828 (1958).

    CAS  PubMed  Google Scholar 

  • Jungas, R. C.: Role of cyclic-3′,5′-AMP in the response of adipose tissue to insulin. Proc. nat. Acad. Sci. (Wash.) 56, 757–763 (1966).

    Article  CAS  Google Scholar 

  • —, and E. G. Ball: Studies on the metabolism of adipose tissue XII. The effects of insulin and epinephrine on free fatty acid and glycerol production in the presence and absence of glucose. Biochemistry 2, 383–388 (1963).

    Article  CAS  PubMed  Google Scholar 

  • Keahl, M. E.: The action of insulin on cells. New York: Academic Press 1961.

    Google Scholar 

  • Kuo, J. F.: Comparisons of the effects of bacillus subtilis protease, type VIII (subtilopeptidase A), and insulin on isolated adipose cells. II. Antilipolytic action. J. biol. Chem. 243, 211–215 (1968).

    CAS  PubMed  Google Scholar 

  • Levine, R.: The action of insulin at the cell membrane. Amer. J. Med. 40, 691–694 (1966a).

    Article  CAS  PubMed  Google Scholar 

  • — The place of insulin and glucagon in the regulation of carbohydrate metabolism. In: D-Glucose und verwandte Verbindungen in Medizin und Biologie (Bartelheimer, Heyde u. Thorn, ed.). Stuttgart: Enke 1966b.

    Google Scholar 

  • Müller-Oerlinghausen, B., u. U. Schwabe, A. Hasselblatt, and F. H. Schmidt: Activity of 3′, 5′-AMP phosphodiesterase in liver and adipose tissue of normal and diabetic rats. Life Sci. 7, 593–598 (1968).

    Article  PubMed  Google Scholar 

  • Ottolenghi, A.: Phospholipase activity of rat tissues and its modification by trypsin. Lipids 2, 303–307 (1967).

    Article  CAS  PubMed  Google Scholar 

  • Pätau, K.: Zur statistischen Beurteilung von Messungsreihen (eine t-Tafel). Biol. Zbl. 63, 154 (1943).

    Google Scholar 

  • Rapport, M. M., and N. Alonzo: Photometric determination of fatty acid ester groups in phospholipides. J. biol. Chem. 217, 193–198 (1955).

    CAS  PubMed  Google Scholar 

  • Rieser, P., and C. H. Rieser: Anabolic responses of diaphragm muscle to insulin and to other pancreatic proteins. Proc. Soc. exp. Biol. (N. Y.) 116, 669 (1964a).

    Article  CAS  Google Scholar 

  • — Insulin-catalyzed proteolysis. Biochem. biophys. Res. Commun. 17, 373 to 376 (1964b).

    Article  CAS  Google Scholar 

  • Rodbell, M.: Metabolism of isolated fat cells I. Effects of hormones on glucose metabolism and lipolysis. J. biol. Chem. 239, 375–380 (1964).

    CAS  PubMed  Google Scholar 

  • — Metabolism of isolated fat cells. II. The similar effects of phospholipase C (Clostridium perfringens α-toxin) and of insulin on glucose and amino acid metabolism. J. biol. Chem. 241, 130–139 (1966).

    CAS  PubMed  Google Scholar 

  • —, and A. B. Jones: Metabolism of isolated fat cells III. The similar inhibitory action of phospholipase C (Clostridium perfringens α-toxin) and of insulin on lipolysis stimulated by lipolytic hormones and theophylline. J. biol. Chem. 241, 140–143 (1966).

    CAS  PubMed  Google Scholar 

  • Schultz, G., G. Senft, W. Losert u. R. Sitt: Biochemische Grundlagen der Diazoxyd-Hyperglykämie. Naunyn-Schmiedebergs Arch. Pharmak. exp. Path. 253, 372 (1966).

    Article  CAS  Google Scholar 

  • Senft, G., W. Losert, G. Schultz, R. Sitt u. H. K. Bartelheimer: Ursachen der Störungen im Kohlehydratstoffwechsel unter dem Einfluß sulfonamidierter Diuretica. Naunyn-Schmiedebergs Arch. Pharmak. exp. Path. 255, 369–382 (1966).

    Article  CAS  Google Scholar 

  • — K. Munske, G. Schultz u. M. Hoffmann: Der Einfluß von Hydrochlorothiazid und anderen sulfonamidierten Diuretica auf die 3′, 5′-AMP-Phosphodiesterase-Aktivität in der Rattenniere. Naunyn-Schmiedebergs Arch. Pharmak. exp. Path. 259, 344–359 (1968).

    Article  CAS  Google Scholar 

  • Sneyd, J. G. T., J. D. Corbin, and C. R. Park: The role of cyclic AMP in the action of insulin. Advanc. exp. Med. 2, 367–376 (1968).

    Article  Google Scholar 

  • Standl, E., H. Haslbeck, C.-A. Geser u. H. Mehnert: Untersuchungen zur Frage einer Wechselwirkung von saluretisch wirksamen Thiazidderivaten und Thiamin bei Diabetikern. Klin. Wschr. 46, 1171–1173 (1968).

    Article  CAS  PubMed  Google Scholar 

  • Streubel, J.: Dissertation, Med. Fakultät Berlin (in Vorbereitung).

    Google Scholar 

  • Wiebelhaus, V. D., J. Weinstock, A. R. Maass, F. T. Brennan, G. Sosnowski u. T. Larsen: The diuretic and natriuretic activity of triamterene and several related pteridines in the rat. J. Pharmacol. exp. Ther. 149, 397–403 (1965).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1969 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

von Bruchhausen, F., Streubel, J. (1969). Wirkungen von Amilorid und Triamteren auf die Lipolyse und den durch Enzyme induzierten Glucosetransport isolierter Fettzellen. In: Habermann, E., et al. Naunyn Schmiedebergs Archiv für Pharmakologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-39718-3_21

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-39718-3_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-38809-9

  • Online ISBN: 978-3-662-39718-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics