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Cerebrospinal fluid analysis Clinical neurochemistry

  • E. Stark
  • U. Patzold
  • U. Wurster
  • M. Wick
  • M. Huber
  • W. Fink
  • K. Einhäupl
  • A. Fateh-Moghadam
  • M. Proescholdt
  • W. Enzensberger
  • L. Demisch
  • P.-A. Fischer
  • H. Shoji
  • R. Hondo
  • H. W. Kölmel
  • R. Lange
  • H. Bocklage
  • T. Weber
  • R. Turner
  • M. Burchhardt
  • P. Rieckmann
  • W. Liier
  • Stephan Bamborschke
  • Angelika Porr
  • Brunhilde Rehse-Küpper
  • Achim Kaufhold
  • Andreas Podbielski
  • A. Rolfs
  • I. Weber
  • B. Heidrich
  • B. Wildemann
  • S. Munzinger
  • B. Storch-Hagenlocher
  • H. Steuler

Abstract

Autoimmune phenomena are of major importance in the pathogenesis of the main paraneoplastic diseases in humans. The autoimmune process is probably triggered by oncogenic antigens, which are cross-reactive or identical with certain neural antigens. Despite the known pathomechanism these syndromes are still considered as non-treatable. We report two cases of paraneoplastic cerebellar degeneration, in which intensive immunosuppression with cytostatics lead to considerable neurological improvement.

Keywords

Human Immunodeficiency Virus Type Herpes Simplex Virus Type Progressive Multifocal Leukoencephalopathy Progressive Multifocal Leukoencephalopathy Herpes Simplex Virus Encephalitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1992

Authors and Affiliations

  • E. Stark
    • 1
  • U. Patzold
    • 2
  • U. Wurster
    • 1
  • M. Wick
    • 3
  • M. Huber
    • 3
  • W. Fink
    • 3
  • K. Einhäupl
    • 4
  • A. Fateh-Moghadam
    • 3
  • M. Proescholdt
    • 5
  • W. Enzensberger
    • 5
  • L. Demisch
    • 5
  • P.-A. Fischer
    • 5
  • H. Shoji
    • 6
  • R. Hondo
    • 7
  • H. W. Kölmel
    • 8
  • R. Lange
    • 8
  • H. Bocklage
    • 8
  • T. Weber
    • 9
  • R. Turner
    • 9
  • M. Burchhardt
    • 9
  • P. Rieckmann
    • 9
  • W. Liier
    • 9
  • Stephan Bamborschke
    • 10
  • Angelika Porr
    • 10
  • Brunhilde Rehse-Küpper
    • 10
  • Achim Kaufhold
    • 11
  • Andreas Podbielski
    • 11
  • A. Rolfs
    • 12
  • I. Weber
    • 12
  • B. Heidrich
    • 12
  • B. Wildemann
    • 13
  • S. Munzinger
    • 13
  • B. Storch-Hagenlocher
    • 13
  • H. Steuler
    • 13
  1. 1.Hannover Medical SchoolMunicipal HospitalDeutschland
  2. 2.BraunschweigDeutschland
  3. 3.Institute for Clinical ChemistryMünchen 70Germany
  4. 4.Neurological Department ofKlinikum GroßhadernMunich UniversityMünchen 70Germany
  5. 5.Department of NeurologyUniversity HospitalFrankfurt/MainGermany
  6. 6.First Department (Neurology) of Internal MedicineKurume University of MedicineKurumeJapan
  7. 7.Department of MicrobiologyInstitute of National Public HealthTokyoJapan
  8. 8.Department of Neurology, CharitéHumboldt University BerlinBerlinGermany
  9. 9.Neurologische Klinik und PoliklinikUniversität GöttingenGöttingenGermany
  10. 10.Klinik für NeurologieUniversität zu KölnGermany
  11. 11.Institut für Medizinische MikrobiologieRWTH AachenGermany
  12. 12.Dep of Neurology (Prof. P. Marx), Klinikum SteglitzFU BerlinBerlin 45Germany
  13. 13.Department of NeurologyUniversity HospitalHeidelbergGermany

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