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Prostaglandin-Induced cAMP Synthesis in Peripheral Nerve

  • Peter Kalix

Abstract

Prostaglandins of the E series induce an acceleration of cAMP synthesis in peripheral nerve tissue from several species. For example, exposure to PE 1 increases the cAMP content in calf vagus nerve twofold and in that of the rabbit threefold; PE 2 has a comparable effect. Similarly, PE 1 increases the cAMP synthesis in the superior cervical ganglion of calf, rat and rabbit; in these tissues, however, the presence of a phosphodiesterase inhibitor is required for accumulation of the nucleotide.

Keywords

Adenylate Cyclase Adenylate Cyclase Activity Superior Cervical Ganglion cAMP Content cAMP Formation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • Peter Kalix
    • 1
  1. 1.Département de Pharmacologie de l’UniversitéGenève 4Schweiz

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