The Effect of Acetylcholine and cGMP on Slow Response Action Potential and Contractile Force in Mammalian Atrial Myocardium

  • M. Kohlhardt
  • K. Haap

Abstract

In isolated myocardium from the left atrium of guinea pigs, the effect of acetylcholine (ACh) and 8-Br-cGMP on the slow response action potential and on contractile force was studied. ACh reduced upstroke velocity and overshoot and abbreviated action potential duration.

Keywords

Depression Dexamethasone Acetylcholine Glycoside Pentobarbital 

Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • M. Kohlhardt
    • 1
  • K. Haap
    • 1
  1. 1.Physiological InstituteUniversity of FreiburgFreiburgGermany

Personalised recommendations