Biosynthesis pp 433-438 | Cite as

Pyrrolnitrin: A New Mode of Tryptophan Metabolism

  • Marvin Gorman
  • David H. Lively
Part of the Antibiotics book series (ANTIBIOTICS)

Abstract

Pyrrolnitrin, a new antifungal compound produced by a Pseudomonas culture, was reported by Arima and co-workers (1964). Chemical degradation of the molecule by Imanaka et al. (1965 a) established the structure as 3-chloro-4-(2′-nitro-3′-chlorophenyl)-pyrrole (I); this structure was confirmed by synthesis in the Research Laboratories of Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan (Nakano et al., 1966).

Keywords

Fermentation Tuberculosis Pseudomonas Alkaloid Streptomyces 

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1967

Authors and Affiliations

  • Marvin Gorman
  • David H. Lively

There are no affiliations available

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