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Gramicidins

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Antibiotics

Abstract

Gramicidin, produced by Bacillus brevis, was isolated along with tyrocidine in 1941 (Hotchkiss, 1944) from the crude material described by Dubos (1939). Early preparations were called gramicidin D (Dubos). Later, countercurrent distribution techniques resolved gramicidin into four groups of polypeptides now specifically designated as gramicidins A, B, C, D. Many commercial preparations are mixtures of the Dubos type.

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© 1967 Springer-Verlag Berlin Heidelberg

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Hunter, F.E., Schwartz, L.S. (1967). Gramicidins. In: Gottlieb, D., Shaw, P.D. (eds) Antibiotics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-38439-8_50

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  • DOI: https://doi.org/10.1007/978-3-662-38439-8_50

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-37649-2

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