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Glutamine synthetase and transferase

  • Chapter
Enzyme

Part of the book series: Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse ((HOPPE-SEYLER,volume Teil C))

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Abstract

This enzyme (or enzymes) catalyzes the following reactions:

  1. 1.

    Glutamate + ATP + NH3 → glutamine + ADP + Pi (glutamine synthesis).

  2. 2.

    Glutamine + NH2OH →γ-glutamylhydroxamate + NH3 (glutamyl transfer reaction).

  3. 3.

    Glutamine + H2O → Glutamate + NH3 (arsenolysis of glutamine).

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Author information

Authors and Affiliations

  1. Department of Biochemistry, College of Physicians and Surgeons, Columbia University, New York, USA

    Abel Lajtha

  2. New York State Research Institute for Neurochemistry and Drug Addiction, New York, USA

    Abel Lajtha

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  1. Abel Lajtha
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Editor information

R. A. Alberty G. Bratfisch F. H. Bruns R. Caputto F. Chatagner M. Chiga R. Czok R. Ehrenreich W. Franke H. Gibian D. M. Greenberg H. Hanson W. Hasselbach O. Hoffmann-Ostenhof B. Kassell K. N. v. Kaulla A. S. Keston H. Kröger A. Lajtha M. Laskowski Sr. M. Laskowski Jr. F. Leuthardt S. Lissitzky R. Michel J. F. Morrison R. J. Peanasky G. Pfleiderer G. W. E. Plaut H. Reinauer H. Schievelbein G. Siebert I. Trautschold M. F. Utter H.-H. Weber H. Weil-Malherbe E. Werle

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© 1967 Springer-Verlag Berlin Heidelberg

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Lajtha, A. (1967). Glutamine synthetase and transferase. In: Alberty, R.A., et al. Enzyme. Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse, vol Teil C. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-38359-9_28

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  • DOI: https://doi.org/10.1007/978-3-662-38359-9_28

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-37579-2

  • Online ISBN: 978-3-662-38359-9

  • eBook Packages: Springer Book Archive

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