Abstract
Infectious complications in patients with end-stage renal disease result in significant morbidity and mortality. Uremia is an immunocompromised state which is due to the direct effects of uremic toxins and to indirect factors, e.g., malnutrition, dialysis membranes with their effects on complement system and white blood cells, or vascular access for dialysis providing a portal of entry for microorganisms [1]. Dysfunction of polymorphonuclear cells (PMN) in uremia includes adherence, the first step in neutrophil migration, chemotaxis, phagocytotic capacity, generation of reactive oxygen intermediates, or intracellular killing of bacteria [2].
Keywords
- Phorbol Myristate Acetate
- Phorbol Myristate Acetate
- Uremic Patient
- Uremic Toxin
- Chronic Hemodialysis Patient
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1991 Springer Japan
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Hörl, W.H. (1991). Neutrophil Function in Uremia: Inhibition by Endogenous Plasma Inhibitor(s). In: Hatano, M. (eds) Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-35158-1_31
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DOI: https://doi.org/10.1007/978-3-662-35158-1_31
Publisher Name: Springer, Berlin, Heidelberg
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