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Nephrology pp 303–311Cite as

Ion Transport Abnormalities in the Development of Hypertension

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Abstract

During the last decade mechanisms of ion transport across the cell membrane have been studied by many investigators interested in arterial hypertension [1–4], because ion transport is fundamental in the regulation of body fluids, renal function, hormone secretion and activity, nerve activity, etc. So far, many abnormalities of various ion transport systems have been described in hypertensive rats and in men with “hereditary” forms of hypertension. Such abnormalities regarding Na-K co-transport [5–7], Na/Li countertransport [6,8–10], Na/H countertransport [11,12], Na-K pump [13], passive permeability or leak [14], Ca pump [15], Ca channels [16] etc. have been reported in the literature. Therefore, theoretically, an abnormality of ion transport might be involved in the pathogenesis of “hereditary” or “primary” forms of hypertension.

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Author information

Authors and Affiliations

  1. Nephrology and Hypertension Unit, Department of Science and Biomedical Technology, Ospedale San Raffaele, University of Milan, Via Olgettina 60, Milan, Italy

    Daniele Cusi

  2. Via Forlanini 1/3, Prassis, Research Institute, Settimo Milanese, Milan, Italy

    Barry Barber

Authors
  1. Giuseppe Bianchi
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  2. Daniele Cusi
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  3. Patrizia Ferrari
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  4. Maria Grazia Tripodi
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  5. Barry Barber
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Editor information

Editors and Affiliations

  1. Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan

    Michinobu Hatano M.D. (Professor of Medicine, Director) (Professor of Medicine, Director)

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© 1991 Springer Japan

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Bianchi, G., Cusi, D., Ferrari, P., Tripodi, M.G., Barber, B. (1991). Ion Transport Abnormalities in the Development of Hypertension. In: Hatano, M. (eds) Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-35158-1_25

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  • DOI: https://doi.org/10.1007/978-3-662-35158-1_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-70074-6

  • Online ISBN: 978-3-662-35158-1

  • eBook Packages: Springer Book Archive

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