Abstract
The chromosomal sex-determining mechanism quite obviously depends upon the presence of female-determining factors on one member and of male-determining factors on the other member of the sex chromosome pair. Yet, the exact nature of so-called sex-determining factors remains a riddle. While sex-linked genes are Mendelian genes which behave in a predictable manner, the sex-determining factors are elusive entities which have not permitted close scrutiny.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bedichek-Pipkin, S.: Sex balance in Drosophila melanogaster. Aneuploidy of short regions of Chromosome 3, using the triploid method. Univ. Texas Publ. 5914, 69–88 (1959).
Bridges, C.B.: Triploid intersexes in Drosophila melanogaster. Science 54, 252–254 (1921).
Carr, D. H., M. L. Barr, and E. R. Plunket: A probable XXYY sex-determining mechanism in a mentally defective male with Klinefelter’s syndrome. Canad. med. Assoc. J. 84, 873–877 (1961).
Dobzhansky, T., and J. Schultz: The distribution of sex factors in the X-chromosome of Drosophila melanogaster. J. Genet. 28, 349–386 (1934).
Ford, C. E., D. W. Jones, P. E. Polani, J. C. Almeida, and J. H. Briggs: A sex chromosome anomaly in a case of gonadal dysgenesis (Turner’s syndrome). Lancet I, 711–713 (1959).
Gayral, L., M. Barrand, J. Carrie et L. Candebat: Pseudo-hermaphrodisme a type de “testicular feminisant”: 11 cas. Etude hormonale et etude psychologique. Toulouse Med. 61, 637–647 (1960).
Jacobs, P. A., and J. A. Strong: A case of human intersexuality having a possible XXY sex-determining mechanism. Nature 183, 302 (1959).
Jost, A.: Sur les effects de castration précoce de le embryon male du lapin. C. R. Soc. Biol. 141, 126–129 (1947).
Lebedeff, G. A.: A study of intersexuality in Drosophila virilis. Genetics 24, 553–556 (1939).
Matthey, R.: Le probleme de la determination du sexe chez Acomys selousi de Winton. Cytogenetique du genre Acomys (Rodentia-Murinae). Rev. suisse Zool. 72, 119–144 (1965).
Morgan, T. H., C. B. Bridges, and A. H. Sturtevant: The genetics of Drosophila melanogaster. Biblio. Genet. 2, 1–262 (1925).
Ohno, S., J. Jainchill, and C. Stenius: The creeping vole (Microtus oregoni) as a gonosomic mosaic. I. The OY/XY constitution of the male. Cytogenetics 2, 232–239 (1963).
Patterson, J. T., W. Stone, and S. Bedichek: Further studies on X-chromosome balance in Drosophila melanogaster. Genetics 22, 407–426 (1937).
Russell, L. B., and E. H. Chu: An XXY-male in the mouse. Proc. Nat. Acad Sci. (Wash.) 47, 571–575 (1961).
Sturtevant, A. H.: A gene in Drosophila melanogaster that transforms females into males. Genetics 30, 297–299 (1945).
Welshons, W. J., and L. B. Russell: The Y-chromosome as the bearer of male determining factors in the mouse. Proc. Nat. Acad. Sci. (Wash.) 45, 560–566 (1959).
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1966 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Ohno, S. (1966). Elucidation of So-called Sex-determining Factors. In: Sex Chromosomes and Sex-linked Genes. Monographs on Endocrinology, vol 1 . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-35113-0_14
Download citation
DOI: https://doi.org/10.1007/978-3-662-35113-0_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-34792-8
Online ISBN: 978-3-662-35113-0
eBook Packages: Springer Book Archive