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Elucidation of So-called Sex-determining Factors

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Sex Chromosomes and Sex-linked Genes

Part of the book series: Monographs on Endocrinology ((ENDOCRINOLOGY,volume 1 ))

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Abstract

The chromosomal sex-determining mechanism quite obviously depends upon the presence of female-determining factors on one member and of male-determining factors on the other member of the sex chromosome pair. Yet, the exact nature of so-called sex-determining factors remains a riddle. While sex-linked genes are Mendelian genes which behave in a predictable manner, the sex-determining factors are elusive entities which have not permitted close scrutiny.

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References

  • Bedichek-Pipkin, S.: Sex balance in Drosophila melanogaster. Aneuploidy of short regions of Chromosome 3, using the triploid method. Univ. Texas Publ. 5914, 69–88 (1959).

    Google Scholar 

  • Bridges, C.B.: Triploid intersexes in Drosophila melanogaster. Science 54, 252–254 (1921).

    Article  PubMed  CAS  Google Scholar 

  • Carr, D. H., M. L. Barr, and E. R. Plunket: A probable XXYY sex-determining mechanism in a mentally defective male with Klinefelter’s syndrome. Canad. med. Assoc. J. 84, 873–877 (1961).

    PubMed  CAS  Google Scholar 

  • Dobzhansky, T., and J. Schultz: The distribution of sex factors in the X-chromosome of Drosophila melanogaster. J. Genet. 28, 349–386 (1934).

    Article  Google Scholar 

  • Ford, C. E., D. W. Jones, P. E. Polani, J. C. Almeida, and J. H. Briggs: A sex chromosome anomaly in a case of gonadal dysgenesis (Turner’s syndrome). Lancet I, 711–713 (1959).

    Article  Google Scholar 

  • Gayral, L., M. Barrand, J. Carrie et L. Candebat: Pseudo-hermaphrodisme a type de “testicular feminisant”: 11 cas. Etude hormonale et etude psychologique. Toulouse Med. 61, 637–647 (1960).

    PubMed  CAS  Google Scholar 

  • Jacobs, P. A., and J. A. Strong: A case of human intersexuality having a possible XXY sex-determining mechanism. Nature 183, 302 (1959).

    Article  PubMed  CAS  Google Scholar 

  • Jost, A.: Sur les effects de castration précoce de le embryon male du lapin. C. R. Soc. Biol. 141, 126–129 (1947).

    CAS  Google Scholar 

  • Lebedeff, G. A.: A study of intersexuality in Drosophila virilis. Genetics 24, 553–556 (1939).

    PubMed  CAS  Google Scholar 

  • Matthey, R.: Le probleme de la determination du sexe chez Acomys selousi de Winton. Cytogenetique du genre Acomys (Rodentia-Murinae). Rev. suisse Zool. 72, 119–144 (1965).

    PubMed  CAS  Google Scholar 

  • Morgan, T. H., C. B. Bridges, and A. H. Sturtevant: The genetics of Drosophila melanogaster. Biblio. Genet. 2, 1–262 (1925).

    Google Scholar 

  • Ohno, S., J. Jainchill, and C. Stenius: The creeping vole (Microtus oregoni) as a gonosomic mosaic. I. The OY/XY constitution of the male. Cytogenetics 2, 232–239 (1963).

    Article  PubMed  CAS  Google Scholar 

  • Patterson, J. T., W. Stone, and S. Bedichek: Further studies on X-chromosome balance in Drosophila melanogaster. Genetics 22, 407–426 (1937).

    PubMed  CAS  Google Scholar 

  • Russell, L. B., and E. H. Chu: An XXY-male in the mouse. Proc. Nat. Acad Sci. (Wash.) 47, 571–575 (1961).

    Article  PubMed  CAS  Google Scholar 

  • Sturtevant, A. H.: A gene in Drosophila melanogaster that transforms females into males. Genetics 30, 297–299 (1945).

    PubMed  CAS  Google Scholar 

  • Welshons, W. J., and L. B. Russell: The Y-chromosome as the bearer of male determining factors in the mouse. Proc. Nat. Acad. Sci. (Wash.) 45, 560–566 (1959).

    Article  PubMed  CAS  Google Scholar 

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© 1966 Springer-Verlag Berlin Heidelberg

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Ohno, S. (1966). Elucidation of So-called Sex-determining Factors. In: Sex Chromosomes and Sex-linked Genes. Monographs on Endocrinology, vol 1 . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-35113-0_14

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  • DOI: https://doi.org/10.1007/978-3-662-35113-0_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-34792-8

  • Online ISBN: 978-3-662-35113-0

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