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Vergleichende Untersuchungen über den Stoffwechsel der verschiedenen Arten und Varianten der Gattung Mycobacterium

(Möglichkeiten einer Stoffwechselsystematik der Tuberkelbakterien)

  • Conference paper
Jahresbericht Borstel

Part of the book series: Tuberkulose-Forschungsinstitut Borstel ((TBC BORSTEL,volume 1956/57))

Zusammenfassung

Die durch die gegenwärtig vorwiegend chemotherapeutische Behandlung der Tuberkulose bedingte Ausweitung und Intensivierung der bakteriologischen Arbeit hat zur Entdeckung neuer, bisher nicht bekannter Formen, Varianten und Arten des Mycobacteriums geführt, die, obwohl größtenteils nicht pathogen für das Meerschweinchen in ihrer Morphologie und ihrem kulturellen Verhalten den echten Tuberkelbakterien in vielen Fällen so ähnlich sind, daß eine Differenzierung von diesen erhebliche Schwierigkeiten bereitet. Die Drogenresistenz, vor allem die mit der Isoniazidresistenz gekoppelte Virulenzschwächung der Tuberkelbakterien hat zu einer weiteren Erschwerung der differential-diagnostischen Arbeit geführt. Es ist mit den heute bekannten und allgemein verwendeten Verfahren zur Differenzierung der einzelnen Arten und Varianten der Gattung Mycobacterium nicht mehr möglich, bestimmte apathogene oder auch pathogene, „saprophytäre“ Mycobakterien mit Sicherheit von isoniazidresistenten, virulenzgeschwächten Tuberkelbakterienstämmen oder gar von isoniazidresistenten BCG-Stämmen bzw. von avirulenten humanen Stämmen des Ra-Typs zu unterscheiden.

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Literatur

  1. Abraham, E. P.: Penicillinase. In J. B. Sumner u. K. Myrbäck, The Enzymes, Bd. 1, Teil 2, S. 1170. 1951.

    CAS  Google Scholar 

  2. Abraham, E. P., and E. Chain: An enzyme from bacteria able to destroy penicillin. Nature (Lond.) 146, 837 (1940).

    CAS  Google Scholar 

  3. Abraham, E. P., E. Chain, C. M. Fletcher, H. W. Florey, A. D. Gardner, N. G. Heatly and M. A. Jennings: Further observations on penicillin. Lancet 1941, 177.

    Google Scholar 

  4. Aeschlimann, J. A., u. A. Stempel: Heterocyclische Tuberkulosemittel. Amer. Pat. 2655279 v. 2. 7. 1952; ausgeg. 5. 1. 1954, Hoffmann-La Roche, Inc. Nutley.

    Google Scholar 

  5. Aksianzew, M. F.: On the oxidation-reduction potential of some strains ob tubercle bacilli in relation to their virulence. Z. Tbk. 68, 249 (1933).

    CAS  Google Scholar 

  6. Albert, A., and C. W. Rees: The destruction of isonicotinic acid hydrazide in the presence of haemin. Biochemic. J. 61, 128 (1955).

    CAS  Google Scholar 

  7. Alexander-Jackson, E.: Atypical Form of Pathogenic Mycobacteria. Internat. Rec. Med. Gen-Pract. Clin. 167, 389 (1954).

    CAS  Google Scholar 

  8. Altemeier, W. A.: Inactivation of Penicillin by various gram negative bacteria. Surg. etc. 81, 379 (1945).

    Google Scholar 

  9. Anderson, K. F., M. B. King, R. Knox e P. Meadow: The in vitro Action of Isoniazid. VI. Congr. Internat. di Microbiologia, Roma, 6.–12. Sept. 1953. Riassunte della Comuniazioni 139, 215. 1953.

    Google Scholar 

  10. Andrejew, A.: Sur la décomposition de l’eau oxygénée par le bacille de Koch. Ann. Inst. Pasteur 72, 833 (1946).

    Google Scholar 

  11. Andrejew, A.: Les besoins en oxygène du bacille tuberculeux aviaire. C. r. Soc. Biol. Paris 141, 751 (1947).

    Google Scholar 

  12. Andrejew, A.: Effet du benzoate et du salicylate sur la respiration des bacilles tuberculeux virulents et avirulents. Ann. Inst. Past. 81, 550 (1951).

    CAS  Google Scholar 

  13. Arnold, A., C. B. Schreffler and S. T. Lipsius: Chemical determination of nicotinic acid. Industr. Engin. Chem. 13, 62 (1941).

    CAS  Google Scholar 

  14. Aronson, J. D., S. L. Ehrlich and W. Flagg: Effects of isonicotinic acid derivatives on tubercle bacilli. Proc. Soc. Exper. Biol. a. Med. 80, 259 (1952).

    CAS  Google Scholar 

  15. Attz, M., u. H. Weyland: Über die Selbstherstellung proteolysierter Nährbodengrundlagen. Zbl. Bakter. I Orig. 159, 537 (1953).

    CAS  Google Scholar 

  16. Barber, M.: Staphylococcal infection due to Penicillin-resistant strains. Brit. Med. J. 1947 II, 863.

    Google Scholar 

  17. Barber, M.: Coagulase-positive Staphylococci resistant to penicillin. J. of Path. 59, 373 (1947).

    CAS  Google Scholar 

  18. Barber, M.: The incidence of penicillin-sensitive variant colonies in penicillinase-producing strains of Staph. pyogenes. J. Gen. Microbiol. 3, 274 (1949).

    PubMed  CAS  Google Scholar 

  19. Barber, M.: The effect of serial passages in other antibiotics on penicillinase-producing staphylococci. J. Gen. Microbiol. 8, 104 (1953).

    PubMed  CAS  Google Scholar 

  20. Barber, M.: Antibiotic-resistant Staphylococcal Variants. Adaptation in Microorganisms. III. Symp. of the Society f. General Microbiology, April 1953, London, S. 235. Cambridge: University Press 1953.

    Google Scholar 

  21. Barclay, W. R., R. H. Ebert and D. Koch-Weser: Mode of action of isoniazid. Amer. Rev. Tbc. 67, 490 (1953).

    CAS  Google Scholar 

  22. Barnes, J. M.: Penicillin and B. anthracis. J. of Path. 59, 113 (1947).

    CAS  Google Scholar 

  23. Barnett, M., R. M. Busby and D. A. Mitchison: Tubercle bacilli resistant to isoniazid. Virulence and response to treatment with isoniazid in guineapigs and mice. Brit. J. Exper. Path. 34, 568 (1953).

    CAS  Google Scholar 

  24. Barnett, M., S. R. Bushby, R. Goulding, R. Knox and J. M. Robson: Antituberculous activity of cyanacetic acid hydrazide. Brit. Med. J. 1955, No 4940, 647.

    Google Scholar 

  25. Barry, V. C., M. L. Conalty, J. M. Donneny, E. E. Gaffney and F. Winder: Studies on isoniazid-resistant strains of Mycobacterium tuberculosis. I. Growth requirements of strains resistant to 100 micrograms of isoniazid per milliliter. Amer. Rev. Tbc. 71, 785 (1955).

    CAS  Google Scholar 

  26. Baudet, P., u. G. Hagemann: Purification de la pénicillinase de Bacillus cereus. Experientia (Basel) 10, 374 (1954).

    CAS  Google Scholar 

  27. Behrens, O. K., and L. Garrison: Inhibitors for pénicillinase. Arch. of Biochem. 27, 94 (1950).

    CAS  Google Scholar 

  28. Bellamy, W. D., and J. W. Klimek: Some properties of penicillinresistant Staphylococci. J. Bacter. 55, 153 (1948).

    CAS  Google Scholar 

  29. Benedict, T. G., W. G. Schmidt and R. D. Coghill: Penicillin. VII. Pénicillinase. Arch. of Biochem. 8, 377 (1945).

    CAS  Google Scholar 

  30. Bernard, E., B. Kreis and E. Le Joubioux: Sur les bacilles tuberculeux de faible virulence isolés après traitement par l’isoniazide. Rev. Tbc. 19, 1113 (1955).

    CAS  Google Scholar 

  31. Bernheim, F.: The effect of salicylat on the oxygen uptake of the tubercle bacillus. Science (Science) 92, 204 (1940).

    CAS  Google Scholar 

  32. Bernheim, F.: The effect of various substances on the oxygen uptake of the tubercle bacillus. J. Bacter. 41, 387 (1941).

    CAS  Google Scholar 

  33. Bernheim, F.: The oxidation of benzoic acid and related substances by certain mycobacteria. J. of Biol. Chem. 143, 383 (1942).

    CAS  Google Scholar 

  34. Bernheim, F.: Metabolism of Mycobacteria. Fortschr. Tbk.forsch. 4, 5 (1951).

    Google Scholar 

  35. Bethge, J., K. Soehring u. R. Tschesche: Über die Rolle des Wasserstoff-Peroxyds bei der Inhibition nach Dold. Z. Naturforsch. 2b, 12 (1947).

    Google Scholar 

  36. Bethge, J., K. Soehring und R. Tschesche: Über die Rolle des Wasserstoff-Peroxyds bei der Inhibition nach Dold. II. Mitt. Anteil des H2O2 an der Hemmung des Bakterienwachstums durch menschlichen Speichel. Z. Naturforsch. 3b, 330 (1948).

    CAS  Google Scholar 

  37. Bingold, K., u. W. Lang: Die Bakterienkatalase. Studien über ihr Wesen und ihre Bedeutung. Zbl. Bakter. I Orig. 163, 357 (1955).

    CAS  Google Scholar 

  38. Bird, O. D.: Vitamin content of tubercle bacilli. Nature (Lond.) 159, 33 (1947).

    CAS  Google Scholar 

  39. Blair, J. E., M. Carr and J. Buchman: The Action of Penicillin on Staphylococci. J. of Immun. 52, 281 (1946).

    CAS  Google Scholar 

  40. Bloch, H.: Enzymatic characteristics of suspensions of different Mycobacteria. Amer. Rev. Tbc. 61, 270 (1950).

    Google Scholar 

  41. Bloch, H.: Experimentelle Untersuchungen zur Virulenz der Tuberkelbazillen. Schweiz, med. Wschr. 1951, 37.

    Google Scholar 

  42. Bloch, H., and H. Noll: Studies on the virulence of tubercle bacilli: Variations in virulence effected by Tween 80 and thiosemicarbazone. J. of Exper. Med. 97, 1 (1953).

    CAS  Google Scholar 

  43. Bloch, H., D. Widelock and L. R. Peizer: Susceptibility to isoniazid and pathogenicity of tubercle bacilli. Amer. Rev. Tbc. 68, 734 (1953).

    CAS  Google Scholar 

  44. Bönicke, R.: Eine mikrobiologische Methode zur quantitativen Bestimmung von Isonicotinsäurehydrazid. Arch. exper. Path. u. Pharmakol. 216, 490 (1952).

    Google Scholar 

  45. Bönicke, R.: Die Ursachen des Antagonismus INH-Hämin. Naturwiss. 41, 377 (1954).

    Google Scholar 

  46. Bönicke, R.: Über die Bedeutung des Hämins für die Vermehrung der Tuberkelbakterien in synthetischen Nährsubstraten. Naturwiss. 41, 378 (1954).

    Google Scholar 

  47. Bönicke, R.: Die H2O2-Empfindlichkeit INH-sensibler und-resistenter Tuberkelbakterienstämme. Naturwiss. 41, 577 (1954).

    Google Scholar 

  48. Bönicke, R.: Die Vermehrung isoniazidresistenter Varianten des Tb-Bakteriums in Gegenwart von Metallkomplexverbindungen des Chlorophyllins. Z. Hyg. 142, 436 (1956).

    Google Scholar 

  49. Bönicke, R.: Die Katalaseaktivität INH-sensibler und-resistenter Mycobacterien und ihre Hemmbarkeit durch INH. Naturwiss. 41, 430 (1954).

    Google Scholar 

  50. Bönicke, R.: Untersuchungen über die antikatalatische Wirkung des Isoniazids bei Mycobakterien. Z. Hyg. 142, 347 (1956).

    Google Scholar 

  51. Bönicke, R.: Die bakteriotoxische Wirkung des Wasserstoffsuperoxyds in Gegenwart von Isonicotinsäurehydrazid (INH) unter besonderer Berücksichtigung INH-sensibler und-resistenter Tuberkelbakterienstämme. Z. Hyg. 142, 339 (1956).

    Google Scholar 

  52. Bönicke, R.: Katalaseaktivität, Virulenz und Isoniazidempfindlichkeit der Tuberkulosebakterien. Beitr. Klin. Tbk. 117, 171 (1957).

    Google Scholar 

  53. Bönicke, R.: The classification of Mycobacteria with the help of different chemical tests. Bull. Internat. Un. Tbc. 27, 151 (1957).

    Google Scholar 

  54. Bondi, A., and C. C. Dietz: Bacterial penicillinase: production, nature, and significance. J. Bacter. 51, 125 (1946).

    Google Scholar 

  55. Bondi, A., and C. C. Dietz: The susceptibility of penicillinase-producing bacteria to penicillin. I. Factors influencing susceptibility. J. Bacter. 55, 843 (1948).

    CAS  Google Scholar 

  56. Bondi, A., and C. C. Dietz: Penicillin resistant Staphylococci. Proc. Soc. Exper. Biol. a. Med. 60, 55 (1945).

    CAS  Google Scholar 

  57. Bondi, A., and C. C. Dietz: Relationship of penicillinase to the action of penicillin. Proc. Soc. Exper. Biol. a. Med. 56, 135 (1944).

    CAS  Google Scholar 

  58. Bondi, A., and C. C. Dietz: Production of penicillinase by bacteria. Proc. Soc. Exper. Biol. a. Med. 56, 132 (1944).

    CAS  Google Scholar 

  59. Bondi, A., M. De Saint Phalle, J. Kornblum and A. G. Moat: Factors influencing the synthesis of penicillinase by Micrococcus pyogenes. Arch. of Biochem. 53, 348 (1954).

    CAS  Google Scholar 

  60. Bowman, B. U., and W. B. Redmond: The effects of glucose and of oxygen on autolysis of mycobacterium tuberculosis. Amer. Rev. Tbc. 73, 907 (1956).

    CAS  Google Scholar 

  61. Brodersen, R.: Penicillinase from a gramnegative Bacterium. Acta path, scand. (Københ.) 24, 383 (1947).

    CAS  Google Scholar 

  62. Brodhage, H., and A. E. Wilder Smith: Tuberculostatic activity of 2-Pyridyl-(4)-1,3,4-Oxdiazolon-(5), its p-amino-salicylate and other related substances. Brit. J. Tbc. Dis. Chest 1 (1955).

    Google Scholar 

  63. Brodhage, H.: Antituberculous action of 1,3,4-Oxdiazolones. Lancet 1955, 570.

    Google Scholar 

  64. Buhler, V. B., and A. Pollak: Human infection with atypical acid-fast organisms: Report of two cases with pathologic findings. Amer. J. Clin. Path. 23, 363 (1953).

    CAS  Google Scholar 

  65. Christensen, O., A. Jespersen, G. Jonsson u. K. N. Rasmussen: Experimental and clinical studies on Cyanacetic acid hydrazide. Acta tbc. scand. (Kobenh.) 32, 132 (1956).

    CAS  Google Scholar 

  66. Christophersen, J.: Über den Einfluß ultravioletter Strahlung auf den Stoffwechsel von Mycobacterium tuberculosis. (Typus gallinaceus u. bovinus.) Vorratspfl. u. Lebensmittelforsch. 5, 372 (1942).

    CAS  Google Scholar 

  67. Clark, M. E., and E. S. Forrest: Results with oxidation-reduction dyes in the determination of virulence of Mycobacteria. Amer. Rev. Tbc. 68, 786 (1953).

    CAS  Google Scholar 

  68. Cohn, M. L., U. Oda, C. Kovitz and G. Middlebrook: Studies on isoniazid and tubercle bacilli: I. The isolation of isoniazid-resistant mutants in vitro. Amer. Rev. Tbc. 70, 465 (1954).

    CAS  Google Scholar 

  69. Cohn, M. L., C. Kovitz, U. Oda and G. Middlebrook: Studies on isoniazid and tubercle bacilli: II. The growth requirements, catalase activities, and pathogenic properties of isoniazid resistant mutants. Amer. Rev. Tbc. 70, 641 (1954).

    CAS  Google Scholar 

  70. Corper, H. J., and V. D. James: Enzymatic reactions of Mycobacterium tuberculosis and the action of Streptomycin. Amer. Rev. Tbc. 65, 722 (1952).

    CAS  Google Scholar 

  71. Cronheim, G., M. E. Baird und W. N. Dannenburg: Studies with penicillinase in the presence of sulfonamides. Arch. of Biochem. 23, 394 (1949).

    CAS  Google Scholar 

  72. Deinse, F. van: Une souche de bacilles tuberculeux de type bovin difficile à classer. Ann. Inst. Pasteur 72, 241 (1946).

    Google Scholar 

  73. Desbordes, J., et E. Fournier: Contribution à l’étude de la physiologie des bacilles acido-alcoolo-résistants. II. L’équipement enzymatique, la virulence et les indicateurs colorés de pH. Ann. Inst. Pasteur 79, 210 (1950).

    CAS  Google Scholar 

  74. Desbordes, J., et E. Fournier: A propos de la fixation des colorants basiques par les Mycobactéries. Réduction enzymatique du bleu de méthylène par la bacille de la fléole. C. r. Soc. Biol. Paris 145, 1862 (1951).

    PubMed  CAS  Google Scholar 

  75. Desbordes, J., and E. Fournier: Oxidation-reduction dyes for the determination of virulence of mycobacteria in vitro. Amer. Rev. Tbc. 66, 382 (1952).

    CAS  Google Scholar 

  76. Desbordes, J., et E. Fournier: Études de physiologie bactérienne. La virulence des Mycobactéries. — Traveaux récents. Revue d’Immun. 18, 50 (1954).

    CAS  Google Scholar 

  77. Desbordes, J., et E. Fournier: Action des substances colorantes sur les Mycobactéries. I. Colorants basique. Étude de la cinétique de la réaction. Ann. Inst. Pasteur 86, 657 (1954).

    CAS  Google Scholar 

  78. Desbordes, J., E. Fourrier et D. Alix: Action des substances colorantes sur les mycobactéries. II. Colorants basiques (suite). Influence du pH. Ann. Inst. Pasteur. 88, 120 (1955).

    CAS  Google Scholar 

  79. Desbordes, J., E. Fournier et D. Alix: Action des substances colorantes sur les Mycobactéries. III. Colorants basiques (suite). Influence du lavage préalable avec différents solvants des lipides. Ann. Inst. Pasteur 88, 240 (1955).

    CAS  Google Scholar 

  80. Desbordes, J., E. Fournier et D. Alix: Action des substances colorantes sur les Mycobactéries. IV. Colorants acides. Influence du pH. Ann. Inst. Pasteur 88, 719 (1955).

    CAS  Google Scholar 

  81. Dietz, C., and A. Bondi: The susceptibility of penicillinase producing bacteria to penicillin. II. The effect of Sodium-Azide. J. Bacter. 55, 849 (1948).

    CAS  Google Scholar 

  82. Drea, W. F., and A. Andrejew: The metabolism of the Tubercle bacillus. Springfield, Ill.: Ch. C. Thomas 1953.

    Google Scholar 

  83. Dubos, R. J., and G. Middlebrook: Cytochemical reaction of virulent tubercle bacilli. Amer. Rev. Tbc. 58, 698 (1948).

    CAS  Google Scholar 

  84. Duthie, E. S.: The production of stable potent preparations of penicillinase. J. Gen. Microbiol. 12, 370 (1947).

    Google Scholar 

  85. Duthie, E. S.: The production of penicillinase by organism of the subtilis group. Brit. J. Exper. Path. 25, 96 (1944).

    CAS  Google Scholar 

  86. Eadie, G. S., F. Bernheim and R. J. Fitzgerald: The kinetics of the oxidation of benzoic acid by certain mycobacteria. J. of Biol. Chem. 176, 857 (1948).

    CAS  Google Scholar 

  87. Ebina, T., S. Kasai, M. Ishikawa, H. Ishikawa, M. Kitamura, H. Kumagai und M. Matsuda: Studies of methods of assaying BCG Vaccine with enzymes. Sci. Rep. Res. Inst. Tohuku Univ. 2, 1 (1950).

    Google Scholar 

  88. Ebina, T., T. Ito, E. Yakuwa, K. Ito, Y. Takase, A. Ebina und Y. Umeta: Recent studies on freeze-dried BCG Vaccine. Acta tbc. scand. (Københ.) 29, 279 (1954).

    CAS  Google Scholar 

  89. Ebina, T., S. Kasai, M. Isikawa, H. Isikawa, M. Kitamura, H. Kumagai, M. Matuda, K. Ito and Y. Umeda: Studies on the enzyme action in BCG (Application of enzyme in assaying the BCG Vaccine). Jap. J. Tbc. 2, 256 (1954).

    CAS  Google Scholar 

  90. Edson, N. L.: The intermediary metabolism of the mycobacteria. Bacter. Rev. 15, 147 (1951).

    CAS  Google Scholar 

  91. Engbaek, H. Chr.: Differentiation between tubercle bacilli and acid-fast saprophytes for diagnostic purposes. Acta path, scand. (Cøpenh.) 34, 68 (1954).

    CAS  Google Scholar 

  92. Eriksen, K. R.: Studies on the action of penicillin on some rod-shaped, penicillinase-producing bacteria. Acta path. Scand. (Cøpenh.) 23, 489 (1946).

    Google Scholar 

  93. Eriksen, K. R., u. D. Hansen: Observations on the extracellular nature of Staphylococcal penicillinase. Acta path, scand. (Cøpenh.) 35, 169 (1954).

    CAS  Google Scholar 

  94. Fairbrother, R. W., L. Parker and B.R. Eaton: The stability of penicillinase-producing strains of Staphylococcus aureus. J. Gen. Microbiol. 10, 309 (1954).

    PubMed  CAS  Google Scholar 

  95. Fairbrother, R. W.: Mixed Staphylococcal Infections. The development of penicillin-resistant strains. Lancet 1956 I, 716.

    Google Scholar 

  96. Falkmer, St., A. Lind and L. Ploman: Fatal tuberculosis from BCG vaccination. Acta paediatr. (Stockh.) 44, 219 (1955).

    CAS  Google Scholar 

  97. Fallin, J. R., R. A. Patnode and A. K. Hudgins: Toxic effect of penicillin on the culture of tubercle bacilli. Amer. J. Clin. Path. 22, 703 (1952).

    CAS  Google Scholar 

  98. Feinstein, L.: A quick test for flour enrichment. Science (Lancaster, Pa.) 101, 675 (1945).

    CAS  Google Scholar 

  99. Fenner, F.: The pathogenic behavior of Mycobacterium ulcerans and Mycobacterium balnei in the mouse and the developing chick embryo. Amer. Rev. Tbc. 73, 650 (1956).

    CAS  Google Scholar 

  100. Fernandez, O., u. T. Garmándia: Über die Katalasebildung von B. coli und ihren Differentialwert. Z. Hyg. 108, 329 (1928).

    CAS  Google Scholar 

  101. Finlayson, M. K., and N. L. Edson: The Catalase Activity of Mycobacteria. Proc. Roy. Soc. New Zealand 77, 284 (1949).

    CAS  Google Scholar 

  102. Fischer, H., and M. Strell: Naturfarbstoffe. IV. Chlorophyll. In: Naturforschung und Medizin in Deutschland 1939–1946, Bd. 39, Biochemie, Teil I, S. 141. Herausgeg. von R. Kuhn. Wiesbaden: Dieterichsche Verlagsbuchhandlung 1947.

    Google Scholar 

  103. Fisher, M. W.: The altered growth characteristics of isoniazid-resistant tubercle bacilli. Amer. Rev. Tbc. 66, 626 (1952).

    CAS  Google Scholar 

  104. Fisher, M. W.: The antagonism of the tuberculostatic action of isoniazid by hemin. Amer. Rev. Tbc. 69, 469 (1954).

    CAS  Google Scholar 

  105. Fisher, M. W.: Hemin as a growth factor for certain isoniazid-resistant strains of Mycobacterium tuberculosis. Amer. Rev. Tbc. 69, 797 (1954).

    CAS  Google Scholar 

  106. Fisher, M. W.: Revival of Tubercle bacilli after prolonged in vitro exposure to isoniazid. Proc. Soc. Exper. Biol. a. Med. 85, 538 (1954).

    CAS  Google Scholar 

  107. Fitzgerald, R. J., and F. Bernheim: The effect of salicylic acid on the growth, morphology and virulence of Mycobact. tuberculosis. Amer. Rev. Tbc. 58, 210 (1948).

    CAS  Google Scholar 

  108. Fitzgerald, R. J., and F. Bernheim: The effect of sodium fluoride on the metabolism of certain mycobacteria. J. Bacter. 55, 677 (1948).

    CAS  Google Scholar 

  109. Fitzgerald, R. J., F. Bernheim and D. B. Fitzgerald: The inhibition by streptomycin of adaptive enzyme formation in mycobacteria. J. of Biol. Chem. 175, 195 (1948).

    CAS  Google Scholar 

  110. Fitzgerald, R. J., F. Bernheim und D. B. Fitzgerald: The effect of various compounds on adaptive enzyme formation in mycobacteria. Arch. of Biochem. 20, 83 (1949).

    CAS  Google Scholar 

  111. Fitzgerald, R. J., and F. Bernheim: The effect of streptomycin on the metabolism of benzoic acid by certain mycobacteria. J. Bacter. 54, 671 (1947).

    CAS  Google Scholar 

  112. Forbes, B. R., J. S. Wannan and W. B. Kirkland: Indolent cutaneous ulceration due to infection with Mycobacterium ulcerans. Med. J. Austral. 41, 475 (1954).

    PubMed  CAS  Google Scholar 

  113. Franke, W., u. A. Schillinger: Zum Stoffwechsel der säurefesten Bacterien. I. Mitt. Orientierende aerobe Reihenversuche. Biochem. Z. 315, 313 (1944).

    Google Scholar 

  114. Franke, W., Li-Tsound Lee u. D. Kibat: Zum Stoffwechsel der säurefesten Bakterien. II. Mitt. Über das Verhalten der ungesättigten Fettsäuren. Biochem. Z. 319, 263 (1949).

    PubMed  CAS  Google Scholar 

  115. Freerksen, E.: Biologische Wirkungen des Isonicotinsäurehydrazids. Jahresbericht 1952/53 Tuberkulose-Forschungsinstitut Borstel, S. 192. Berlin: Springer 1954.

    Google Scholar 

  116. Freerksen, E., and G. Meissner: Diagnostische und biologische Probleme der isoniazid-resistenten Tuberkelbazillen. Bull. Inter. Un. Tbc. 26, 240 (1956).

    Google Scholar 

  117. Fujita, A., u. T. Kodama: Manometrische Bestimmung der Katalase. Biochem. Z. 232, 20 (1931).

    CAS  Google Scholar 

  118. Gale, G. R.: The oxidation of benzoic acid by mycobacteria. I. Metabolic pathways in Mycobacterium tuberculosis, Mycobacterium butyricum and Mycobacterium phlei. J. Bacter. 63, 273 (1952).

    CAS  Google Scholar 

  119. Gale, G. R.: The oxidation of benzoic acid by Mycobacteria. II. The metabolism of postulated intermediates in the benzoate oxidation chain by four avirulent and two virulent organism. J. Bacter. 64, 131 (1952).

    CAS  Google Scholar 

  120. Gaussee, M. Ch.: L’évolution de la chimiothérapie de la tuberculose. Ann. pharmac. franc. 12, 146 (1947).

    Google Scholar 

  121. Ghoroury, A. A. A.: A new method for detecting penicillinase production by staphylococci. Science (Lancaster, Pa.) 115, 20 (1952).

    Google Scholar 

  122. Gibson, J. B.: Infection of the lungs by „saprophytic” mycobacterium in achalasia of the cardia, with report of a fatal case showing lipoid pneumonia due to milk. J. of Path. 65, 239 (1953).

    CAS  Google Scholar 

  123. Gilson, B. St. C., and R. F. Parker: Staphylococcal penicillinase: Characteristics of the enzyme and its distribution. J. Bacter. 55, 801 (1948).

    CAS  Google Scholar 

  124. Glavind, J., u. S. Hartman: Some observations on the oxidation of easily oxidizable substances by peroxides of fats and fatty acids. Acta chem scand. (Cøpenh.) 3, 914 (1949).

    CAS  Google Scholar 

  125. Gorini, L., and A. Torriani: Biochemistry of Escherichia coli and the production of penicillinase. Nature (Lond.) 160, 332 (1947).

    CAS  Google Scholar 

  126. Gots, J. S.: Production of Extracellular Penicillin-inactivating Substances associated with Penicillin-Resistance in Staphylococcus aureus. Proc. Soc. Exper. Biol. a. Med. 60, 165 (1945).

    CAS  Google Scholar 

  127. Gray, C. T.: Nature of the action of isonicotinic acid hydrazide on the mycobacteria. VI. Congr. Internat, die Microbiologia, Roma, 6.–12. Sept. 1953. Riassunti delle Comuniazioni 179, 269. 1953.

    Google Scholar 

  128. Greene, R. D., A. Black and F. O. Howland: Microbiological and chemical Assay of nicotinic acid in B complex products. Industr. Engin. Chem. 15, 77 (1943).

    CAS  Google Scholar 

  129. Grumbach, F., B. Sureau et F. Boyer: La pénicillinase, conditions de production. Étude de l’activité. Ann. Inst. Pasteur 74, 12 (1948).

    CAS  Google Scholar 

  130. Grumbach, F., et F. Boyer: Méthodes de titrage de la pénicillinase. Ann. Inst. Pasteur. 74, 66 (1948).

    Google Scholar 

  131. Hafner, R., u. P. Ihm: Über das biochemische Verhalten hoch-und normal-resistenter Tuberkelbakterien und anderer säurefester Mycobakterien. Arzneimittel-Forsch. 6, 513 (1956).

    CAS  Google Scholar 

  132. Hahn, M.: Immunisierungs-und Heilversuche mit den plasmatischen Zellsäften von Bakterien. Münch. med. Wschr. 1897, 1344.

    Google Scholar 

  133. Harper, G. J.: Inhibition of penicillin in routine culture media. Lancet 1943, 569.

    Google Scholar 

  134. Harris, J. O., and F. Binns: α-Aminomethylmuconic acid as a possible precursor of niacin. Nature (Lond.) 179, 475 (1957).

    CAS  Google Scholar 

  135. Hauduroy, P.: Microbiologie générale et technique microbiologique. Lausanne 1947.

    Google Scholar 

  136. Hauduroy, P., et M. Cevey: Importance des réactions cyto-chimiques pour la détermination de la virulence des mycobactéries et intérêt pour la classification. Ann. Inst. Pasteur 84, 1034 (1953).

    CAS  Google Scholar 

  137. Hauduroy, P.: La virulence des Mycobactéries. Rev. d’Immun. 18. 62 (1954).

    CAS  Google Scholar 

  138. Hayaishi, O., and A. Kornberg: Metabolism of Cytosine, Thymine, Uracil, and Barbituric Acid by Bacterial Enzymes. J. of Biol. Chem. 197, 717 (1952).

    CAS  Google Scholar 

  139. Heatly, N. G.: A method for the assay of penicillin. Biochemic. J. 38, 61 (1944).

    Google Scholar 

  140. Henry, E. J., u. R. D. Housewright: Studies on penicillinase. II. Manometric method of assaying penicillinase and penicillin, kinetics of the penicillin-penicillinase reaction, and the effects of inhibitors on penicillinase. J. Biol. Chem. 167, 559 (1947 a).

    PubMed  CAS  Google Scholar 

  141. Heilmeyer, L.: Das Resistenzproblem in der Chemotherapie. Erg. Tbk.forsch. 13, 56 (1956).

    Google Scholar 

  142. Heppel, L. A., and V. T. Porterfield: Metabolism of inorganic nitrite and nitrate esters. I. The coupled oxidation of nitrite by peroxide-forming systems and catalase. J. of Biol. Chem. 178, 549 (1949).

    CAS  Google Scholar 

  143. Hermelink, B.: Lassen sich Smegmabazillen und andere säurefeste Saprophyten mit Sicherheit von Tuberkelbazillen unterscheiden? Dtsch. med. Wschr. 1949, 1144.

    Google Scholar 

  144. Hobby, G. L., and M. H. Dawsen: Bacteriostatic Action of Penicillin on Hemolytic Streptococci in vitro. Proc. Soc. Exper. Biol. a. Med. 56, 178 (1944).

    CAS  Google Scholar 

  145. Hoffmann-Ostenhof, O.: Enzymologie. Wien 1954.

    Google Scholar 

  146. Hofstetter, M.: Die Behandlung der Lungentuberkulose mit dem Haydrazid der Cyanessigsäure (CEH) (Reazide). Schweiz. Z. Tbk. 13, 430 (1956).

    CAS  Google Scholar 

  147. Holloway, W. J. and E. G. Scott: Studies on the staphylococcus. III. Penicillinase production. Delware Med. J. 28, 6 (1956).

    CAS  Google Scholar 

  148. Hollström, E., u. S. Hard: A fatality from BCG-vaccination. Acta dermato-vener. (Stockh.) 33, 159 (1953).

    Google Scholar 

  149. Housewright, R. D. and R. J. Henry: Studies on penicillinase. I. The production, partial purification., and practical application of penicillinase. J. of Biol. Chem. 167, 553 (1947 a).

    CAS  Google Scholar 

  150. Hughes, D.E., E. S. Moss, M. Hood and M. Heuson: Virulence of Mycobacterium tuberculosis. Evaluation of a Test, Neutral Red Indicator. Amer. J. Clin. Path. 24, 621 (1954).

    CAS  Google Scholar 

  151. Hutter, S.: Un inhibiteur de la pénicillinase dans les filtrats de Penicillia producteurs de pénicilline. Biochim. et Biophysica Acta 4, 572 (1950).

    Google Scholar 

  152. Iland, C. M.: The effect of penicillin on the tubercle bacillus. J. of Path. 58, 495 (1946).

    CAS  Google Scholar 

  153. Iland, C. N., and S. Baines: The effect of penicillin on the tubercle bacillus: Tubercle penicillinase. J. of Path. 61, 329 (1949).

    CAS  Google Scholar 

  154. Immerslund, O., u. T. Jonsen: Lupus vulgaris and multiple bone lesions caused by BCG. Acta tbc. scand. (Københ.) 30, 116 (1954).

    Google Scholar 

  155. Irrgang, K., u. U. Dörnbrack: Über das Schicksal des Penicillins im Organismus. II. Mitteilung. Die Reaktivierung von durch Penicillinase inaktiviertem Penicillin. Hoppe-Seylers. Z. 285, 17 (1950).

    CAS  Google Scholar 

  156. Irrgang, K., H. Mara und H. Sachs: Einige Beobachtungen über das Verhalten penicillin-resistenter Mikroorganismen. Z. Naturforsch. 5b, 144 (1950).

    CAS  Google Scholar 

  157. Ishikawa, H.: The studies on the assay of BCG Vaccines with respiration and catalase action. Sci. Rep. Res. Inst. Tohuku Univ. 3, 35 (1951).

    CAS  Google Scholar 

  158. Ito, K.: Studies on the Enzymes of Dried BCG Vaccines (Especially on Katalase and Dehydrogenase). Sci. Rep. Res. Inst. Tohuku Univ. 5, 1 (1953).

    CAS  Google Scholar 

  159. Jensen, J., u. E. Thofern: Chlorhämin (Ferriporphyrinchlorid) als Bakterienwuchsstoff. I. Z. Naturforsch. 8b, 599 (1953).

    CAS  Google Scholar 

  160. Jensen, J., u. E. Thofern: Chlorhämin (Ferriporphyrinchlorid) als Bakterienwuchsstoff. II. Zur Synthese der Häminfermente. Z. Naturforsch. 8b, 604 (1953).

    CAS  Google Scholar 

  161. Jensen, J., u. E. Thofern: Chlorhämin (Ferriporphyrinchlorid) als Bakterienwuchsstoff. III. Competitive Hemmung der Hämatinfermentsynthese. Z. Naturforsch. 8b, 697 (1953).

    CAS  Google Scholar 

  162. Jensen, J., u. E. Thofern: Chlorhämin (Ferriporphyrinchlorid) als Bakterienwuchsstoff. IV. Zum Cytochromsystem von M. pyog. var. aureus. Z. Naturforsch. 9b, 596 (1954).

    CAS  Google Scholar 

  163. Jensen, K. A.: Some remarks concerning attenuated isoniazid-resistant strains of tubercle bacilli. Acta path. scand. (Københ.) 37, 71 (1955).

    CAS  Google Scholar 

  164. Jensen, K. A.: Essai de standardisation des méthodes de Laboratoire. Deuxième rapport de la sous-commission des méthodes de laboratoire. Bull. Internat. Un. Tbc. 24, 96 (1955).

    Google Scholar 

  165. Jensen, J., W. Möller u. E. Thofern: Biologische Penicillin-Inaktivierung ohne Penicillinase. Naturwiss. 41, 404 (1954).

    CAS  Google Scholar 

  166. Jorns, A.: Über Bakterienkatalase. Arch. f. Hyg. 67, 134 (1908).

    CAS  Google Scholar 

  167. Keilin, D., and E. F. Hartree: Catalase, Peroxidase and Metmyoglobin as Catalysts of coupled peroxidatic reactions. Biochemie. J. 60, 310 (1955).

    CAS  Google Scholar 

  168. Keilin, D., and E. F. Hartree: Properties of Catalase. Catalyse of coupled oxidation of alcohols. Biochemic. J. 39, 293 (1945).

    CAS  Google Scholar 

  169. Kirby, W. M. M.: Properties of a penicillin inactivator extracted from pecinillin-resistant staphylococci. J. Clin. Invest. 24, 170 (1945).

    PubMed  CAS  Google Scholar 

  170. Kirby, W. M. M.: Extraction of a highly potent Penicillin Inactivator from Penicillin-resistant Staphylococci. Science (Lancaster, Pa.) 99, 452 (1944).

    CAS  Google Scholar 

  171. Kirby, W. M. M.: Bacteriostatic and lytic actions of penicillin on sensitive an resistant staphylococci. J. Clin. Invest. 24, 165 (1945).

    PubMed  CAS  Google Scholar 

  172. Kitamura, M.: Chemotherapeutic drugs and their effect on the dehydrogenase of tubercle Bacilli. Sci. Rep. Res. Inst. Tohuku Univ. 2, 59 (1950).

    CAS  Google Scholar 

  173. Kitamura, M.: Studies on the Dehydrogenation of BCG. Sci. Rep. Res. Inst. Tohuku Univ. 5, 143 (1953).

    CAS  Google Scholar 

  174. Klimek, J. W., C. J. Cavallito and J. H. Bailey: Induced resistance of Staph. aureus to various antibiotics. J. Bacter. 55, 139 (1948).

    CAS  Google Scholar 

  175. Knox, R.: The effect of Temperature on Enzymic Adaptation, Growth an Drug Resistance. Adaptation in Microorganisms. III. Symp. of the Soecity f. General Microbiology, April 1953, London. S. 184. Cambridge: University Press. 1953.

    Google Scholar 

  176. Knox, R.: Haemin and isoniazid resistance of Mycobact-tuberculosis. J. Gen. Microbiol. 12, 191 (1955).

    PubMed  CAS  Google Scholar 

  177. Knox, R., and R. C. Woodroffe: Haemin-isoniazid interaction and the effect of haemin in „reviving” isoniazid-treated tubercle bacilli. Brit. J. Exper. Path. 36, 425 (1955).

    CAS  Google Scholar 

  178. Knox, R., A. Albert and C. W. Rees: Destruction of Isoniazid in the presence of Haemin. Nature (Lond.) 175, 1085 (1955).

    CAS  Google Scholar 

  179. Knox, R., P. M. Meadow and A. R. H. Worssam: The relationship between the catalase activity, hydrogen peroxide sensitivity, and isoniazid resistance of mycobacteria. Amer. Rev. Tbc. 73, 726 (1956).

    CAS  Google Scholar 

  180. Koch-Weser, D., W. R. Barclay and R. H. Ebert: The influence of Isoniazid and Streptomycin on acid-fastness, tetrazolium reduction, growth, and survival of tubercle bacilli. Amer Rev. Tbc. 71, 556 (1955).

    CAS  Google Scholar 

  181. Kölbel, H.: Zum Wert und Reaktions-Mechanismus des Neutralrot-Testes. Z. Hyg. 143, 387 (1957).

    Google Scholar 

  182. König, W.: Über eine neue, vom Pyridin derivierende Klasse von Farbstoffen. J. prakt. Chem. 69, 105 (1904).

    Google Scholar 

  183. König, W.: Zur Kenntnis der Pyridinfarbstoffe. J. prakt. Chem. 70, 19 (1904).

    Google Scholar 

  184. König, H. B., W. Siefken u. H. A. Offe: Schwefelhaltige Derivate von Pyridincarbonsäuren und davon abgeleitete Verbindungen. Chem. Ber. 87, 825 (1954).

    Google Scholar 

  185. Körlof, B.: Penicillinase-producing aureus staphylococci in a department for burns and their importance in mixed infections. Acta path, scand. (Cøpenh. 35, 402 (1954).

    Google Scholar 

  186. Körnlein, M., u. G. Koch: Penicillinasenachweis mit Procain-Penicillin. Arzneimittel-Forschg. 4, 130 (1954).

    Google Scholar 

  187. Konno, K.: New chemical method to differentiate humantype tubercle bacilli from other Mycobacteria. Sience (Lancaster, Pa.) 124, 985 (1956).

    CAS  Google Scholar 

  188. Korth, E.: Weitere Untersuchungen über die Wirkung von Trypsin auf bakterielle Toxine, Bakterienwachstum, Agglutinine und Penicillinase. Arzneimittel-Forsch. 4, 388 (1954).

    CAS  Google Scholar 

  189. Kramer, M., y F.B. Sträub: Inductive synthesis of penicillinase in cell-free preparations of B. cereus; a preliminary report. Acta pediát. espan. 13, 167 (1955).

    Google Scholar 

  190. Krebs, A.: Diskussionsbemerkung auf der Tuberkulose-Tagung der DDR. Weimar 1956.

    Google Scholar 

  191. Krehl, W. A., F. M. Strong and C. A. Elvehjem: Determination of nicotinic acid. Modifications in the microbiological method. Industr. Engin. Chem. 15, 471 (1943).

    CAS  Google Scholar 

  192. Kreis, B., et E. Le Joubioux: Rapports entre l’activitécatalasique, la résistance a l’isoniazide et le pouvoir pathogène de souches isoniazido-résistantes. Ann. Inst. Past. 92, 190 (1957).

    CAS  Google Scholar 

  193. Krüger-Thiemer, E.: Chemismus der Isoniazidspaltung durch Hämin. Naturwiss. 42, 47 (1955).

    Google Scholar 

  194. Lahelle, O.: Effect of penicillin on certain intestinal rod-shaped bacteria. Penicillinase production in Proteus morgani. Acta path, scand. (Københ.) 25, 444 (1948).

    Google Scholar 

  195. Langenbeck, W.: Die organischen Katalysatoren und ihre Beziehungen zu den Fermenten, 2. Aufl. Berlin-Göttingen-Heidelberg: Springer 1949.

    Google Scholar 

  196. Lamb, F. W.: Direct quantitative determination of nicotinamide in vitamin mixtures. Industr. Engin. Chem. 15, 352 (1943).

    CAS  Google Scholar 

  197. Laser, H.: Peroxidatic Activity of Catalase. Biochemic. J. 61, 122 (1955).

    CAS  Google Scholar 

  198. Lawrence, C. A.: Effect of enzyme preparation upon penicillin I. J. Bacter. 49, 57 (1945a).

    CAS  Google Scholar 

  199. Lawrence, C. A.: Action of clarase upon penicillin. Science (Lancaster, Pa.) 99, 15 (1944).

    CAS  Google Scholar 

  200. Lawrence, C. A.: Effect of enzyme preparations upon penicillin II. J. Bacter. 49, 47 (1945b).

    CAS  Google Scholar 

  201. Lawrence, C.A.: Sterility tests for penicillin. Science (Lancaster, Pa.) 98, 413 (1943).

    CAS  Google Scholar 

  202. Leach, R. H., and F. Fenner: Studies on Mycobact. ulcerans and Mycobact. balnei. III. Growth in the semi-synthetic culture media of Dubos and drug sensitivity in vitro and in vivo. Austral. J. Exper. Biol. a. Med. Sci. 32, 835 (1954).

    CAS  Google Scholar 

  203. Lebek, G.: Über die oxydativen Fermentwirkungen der beiden Säugetiertypen des Mycobacterium tuberculosis. Zbl. Bakter. I Orig. 165, 424 (1956).

    CAS  Google Scholar 

  204. Lehmann, J.: On the effect of isomers of PAS (Para-Amino-Salicylic acid) and related substances on the tuberculostatic effect of PAS. Experientia (Basel) 9, 365 (1949).

    Google Scholar 

  205. Lehmann, J.: Determination of pathogenicity of tubercle bacilli by their intermediate metabolism. Lancet 1946, 14.

    Google Scholar 

  206. Lembke, A.: Untersuchungen an den Erregern der Tuberkulose. Zbl. Bakter. I Orig. 152, 239 (1948).

    Google Scholar 

  207. Lembke, A., H. Frahm und G. Dannenberg: Enzymatische Studien an Mikroben. I. Über die Katalase von B. subtilis. Zbl. Bakter. I Orig. 155, 153 (1950).

    CAS  Google Scholar 

  208. Lembke, A., und H. Menninger: Stoff Wechseluntersuchungen an Mycobacterium tuberculosis. Kieler milchwirtsch. Forschgsber. 4, 41 (1952).

    Google Scholar 

  209. Lembke, A., E. Krüger-Thiemer, R. B. Kohn u. W. Uecker: Untersuchungen über die Isoniazidwirkung auf Microorganismen. Schweiz. Z. Path. u. Bakter. 16, 222 (1953).

    CAS  Google Scholar 

  210. Le Page, G. A., J. F. Morgan and M. E. Campbell: Production and purification o penicillinase. J. of Biol. Chem. 166, 465 (1946).

    Google Scholar 

  211. Lester, V.: Saprophyte acid-fast bacilli as source of error in diagnostic work. Acta tbc. scand. (Københ.) 13, 251 (1939).

    Google Scholar 

  212. Levaditi, C., et J. Henry: La pénicillino-résistance de la Klebsieila pneumoniae (Bacille de Friedländer). C. r. Soc. Biol. Paris 140, 739 (1946).

    Google Scholar 

  213. Linell, F., u. A. Norden: Mycobacterium balnei; a new acid-fast bacillus occurring in swimming pools and capable of producing skin lesions in humans. Acta tbc. scand. (Københ.) Suppl. 33, 1 (1954).

    CAS  Google Scholar 

  214. Long, E. R.: A study in fundamentals of the nutrition of the tubercle bacillus. The utilisation of some amino acid and ammonium salts. Amer Rev. Tbc. 3, 86 (1948).

    Google Scholar 

  215. Luria, S. E.: A test for penicillin sensitivity and resistance in Staphylococcus. Proc. Soc. Exper. Biol. a. Med. 61, 46 (1946).

    CAS  Google Scholar 

  216. MacCallum, P., J. C. Tolhurst, G. Buckle and H. A. Sisous: A new mycobacterial infection in man. J. of Path. 60, 93 (1948).

    CAS  Google Scholar 

  217. Makino, K., F. Itoh and K. Nishi: Dihydroxyanthralinic acid as a precursor of nicotinic acid. Nature (Lond.) 167, 115 (1951).

    CAS  Google Scholar 

  218. Manson, E. E. D., and M. R. Pollock: The thermostability of penicillinase. J. Gen. Microbiol. 8, 163 (1953).

    PubMed  CAS  Google Scholar 

  219. Manson, E. E. D., M. R. Pollock and E. J. Tridgell: An Comparison of the Properties of Penicillinase produced by Bacillus subtilis and Bacillus cereus with and without Addition of Penicillin. J. Gen. Microbiol. 11, 493 (1954).

    PubMed  CAS  Google Scholar 

  220. Marek, A.: Erfahrungen mit der Empfindlichkeitsprüfung von Tbc-Stämmen gegen Cyanessigsäurehydrazid (CEH). Wien. med. Wschr. 1956, 754.

    Google Scholar 

  221. McAdam, J. W. J., J. P. Duguid and S. W. Challinor: Systemic administration of penicillin. Lancet 1944, 336.

    Google Scholar 

  222. McQuarrie, E. B., and A. F. Liebmann: Studies on penicillinase. Arch. of Biochem. 5, 307 (1944).

    CAS  Google Scholar 

  223. Meissner, G.: Isoniazid resistente Tuberkelbacterien. Fortschr. Tbkforsch. 7, 52 (1956).

    Google Scholar 

  224. Meissner, G.: The virulence of isoniazid resistant tubercle bacilli recovered from patients during treatment. Dis. Chest 24, 1 (1954).

    Google Scholar 

  225. Meissner, G., u. R. Bönicke: Die Beziehungen zwischen Katalase-Inaktivierung, Sensibilitätsminderung für Isoniazid und Virulenzschädigung für das Meerschweinchen. Untersuchungen an frisch isolierten Tuberkelbakterienstämmen mit unterschiedlicher, aber jeweils totaler INH-Resistenz. Beitr. Klin. Tbk. 1957.

    Google Scholar 

  226. Melnick, D., and B. L. Oser: Chemical differentiation between niacinamide and niacin in pharmaceutical products. Industr. Engin. Chem. 15, 355 (1943).

    CAS  Google Scholar 

  227. Melnick, D., B. L. Oser and L. Siegel: Chemical determination of nicotinic acid content of flour and bread. Industr. Engin. Chem. 13, 879 (1941).

    CAS  Google Scholar 

  228. Meyer, J., and K. A. Jensen: A fatal case of tuberculosis produced by BCG. Amer. Rev. Tbc. 70, 402 (1954).

    CAS  Google Scholar 

  229. Meyer-Rohn, J.: Über Penicillinase und ihre Inhibitoren. Hautarzt 5, 264 (1954).

    PubMed  CAS  Google Scholar 

  230. Meyn, A.: Die apathogenen Mycobakterien und ihre Wuchsformen auf Tuberkelbakteriennährböden. Z. Hyg. 133, 127 (1951).

    CAS  Google Scholar 

  231. Middlebrook, G., and M. L. Cohn: Some observations of the pathogenicity of isoniazid-resistant variants of tubercle bacilli. Science (Lancaster, Pa.) 118, 297 (1953).

    CAS  Google Scholar 

  232. Middlebrook, G.: Sterilization of tubercle bacilli by isonicotinic acid hydrazide and the incidence of variants resistant to the drug in vitro. Amer. Rev. Tbc. 65, 765 (1952).

    CAS  Google Scholar 

  233. Middlebrook, G.: Isoniazid resistance and catalase activity of tubercle bacilli, a preliminary report. Amer. Rev. Tbc. 69, 471 (1954).

    CAS  Google Scholar 

  234. Middlebrook, G., M. L. Cohn and W. B. Schaefer: Studies on Isoniazid and Tubercle Bacilli. III. The isolation, drug-susceptibility, and catalasetesting of tubercle bacilli from isoniazid-treated patients. Amer. Rev. Tbc. 70, 852 (1954).

    CAS  Google Scholar 

  235. Miller, G. Ph., and M. Bohnhoff: Studies on the action of Penicillin. VI. Further observations on the development of Penicillin-Resistance by Meningococcus in vitro. J. Inf. Dis. 81, 147 (1947).

    CAS  Google Scholar 

  236. Miller, C. Ph., and M. Bohnhoff: Streptomycin Resistance of Gonococci and Meningococci. J. Amer. Med. Assoc. 130, 485 (1946).

    CAS  Google Scholar 

  237. Mitchison, D. A., and J. B. Selkon: The bactericidal activities of antitubercolous drugs. Amer. Rev. Tbc. 73, 109 (1956).

    Google Scholar 

  238. Mitscherlich, E.: Die Differenzierung frisch isolierter Stämme von Mycobacterium tuberculosis hominis und bovis in Kultur-und Kaninchenversuch. Z. Hyg. 134, 375 (1952).

    CAS  Google Scholar 

  239. Molland, J.: Bacterial catalase. A contribution to the discussion of the anaerobic respiration. Acta path. scand. (Københ.) 66, 165 (1947).

    Google Scholar 

  240. Morgan, J. F., and M. E. Campbell: A rapid method for the production and isolation of penicillinase. J. of Biol. Chem. 169, 337 (1947).

    CAS  Google Scholar 

  241. Norden, A., and F. Linell: A new type of pathogenic mycobacterium. Nature (Lond.) 168, 826 (1951).

    CAS  Google Scholar 

  242. North, E. A., and R. Christie: Acquired resistance of staphylococci to the action of penicillin. Med. J. Austral. 1, 176 (1946).

    PubMed  CAS  Google Scholar 

  243. Oeding, P., and I. Hesselberg: Generalized BCG infection in man. II. Bacteriological investigations. Acta Tbc. scand. 29, 180 (1954).

    Google Scholar 

  244. Offe, H. A., W. Siefken u. G. Domagk: Verfahren zur Herstellung von neuen Oxdiazolon-Derivaten. Dtsch. Pat.; Pat.-Schrift Nr. 923722 Kl. 12 p Gr. 9 F 10107 IV c/21 p v.11. 10 1952, ausgeg. 21.2.1955. Farbenfabriken Bayer, Leverkusen-Bayerwerke.

    Google Scholar 

  245. Ortel, S.: Über die Penicillinresistenz der Staphylokokken. II. Mitt. Penicillinase bei Staphylokokken. Zbl. Bakter. I Orig. 162, 201 (1955).

    CAS  Google Scholar 

  246. Ostry, P., M. Kubin, J. Prochazka, J. Kroml u. A. Freslova: Atypická plicni tuberkulosa, vyvolaná fotochromogennimi mykobakteriemi. Rozhl. tbk. 16, 5 (1956).

    Google Scholar 

  247. Pallaske-Eber, R.: Beitrag zur Frage der Typendifferenzierung der Tuberkelbakterien auf Nährböden. Z. Tbk. 68, 42 (1933).

    Google Scholar 

  248. Parker, R. F.: Action of penicillin on Staphylococcus: effect of size of inoculum on the test for sensitivity. Proc. Soc. Exper. Biol. a. Med. 63, 443 (1946).

    CAS  Google Scholar 

  249. Parlett, R., and G. P. Youmans: Antigenic relationships between Mycobacteria as determined by Agar diffusion precipitin techniques. Amer. Rev. Tbc. 73, 637 (1956).

    CAS  Google Scholar 

  250. Patnode, R. A., C. K. Wrinkle and C. Beasley: Evaluation of the oxidation-reduction dye test for the determination of virulence of mycobacteria in vitro. Amer. Rev. Tbc. 69, 599 (1954).

    CAS  Google Scholar 

  251. Peizer, L. R., D. Widelock and S. Klein: Effect of isoniazid on the viability of isoniazid-susceptible and isoniazid-resistant cultures of Mycobacterium tuberculosis. Amer. Rev. Tbc. 69, 1022 (1954).

    CAS  Google Scholar 

  252. Peizer, L.R., and D. Widelock: A colorimetric test for measuring catalase activity of cultures of Mycobacterium tuberculosis. Amer. Rev. Tbc. 71, 305 (1955).

    CAS  Google Scholar 

  253. Pérault, R.: La Penicillinase. Méthodes de préparation et de titrage. C. r. Soc. Biol. Paris 139, 580 (1945).

    PubMed  Google Scholar 

  254. Pérault, R.: La pénicillinase-coli. Variation de sa production en fonction de la souche microbienne, du milieu et du vieillissement des cultures. C. r. Soc. Biol. Paris 139, 581 (1945).

    PubMed  Google Scholar 

  255. Perlstein, D., and A. J. Liebmann: The production of anti-penicillinase immune sera. Science (Lancaster, Pa.) 102, 197 (1945).

    CAS  Google Scholar 

  256. Perret, C. J.: Iodometric assay of penicillinase. Nature (Lond.) 174, 1012 (1954).

    CAS  Google Scholar 

  257. Pinner, M.: Atypical acid-fast microorganisms: Chromogenic acid-fast bacilli from human beings. Amer. Rev. Tbc. 32, 424 (1935).

    Google Scholar 

  258. Pinner, M.: Atypical acid-fast microorganism: IV. Smooth growing tubercle bacilli. Amer. Rev. Tbc. 32, 440 (1935).

    Google Scholar 

  259. Pollak, A., and V. B. Buhler: The cultural characteristics and animal pathogenicity of an atypical acid-fast organism which causes human diseases. Amer. Rev. Tbc. 71, 74 (1955).

    CAS  Google Scholar 

  260. Pollock, M. R.: Penicillinase adaptation in Bacillus cereus: adaptive enzyme formation in the absence of free substrate. Brit. J. Exper. Path. 31, 739 (1950).

    CAS  Google Scholar 

  261. Pollock, M. R.: Penicillinase adaptation in Bacillus cereus: An analysis of three phases in the response of logarithmically growing cultures to induction of penicillinase formation by penicillin. Brit. J. Exper. Path. 33, 587 (1952).

    CAS  Google Scholar 

  262. Pollock, M. R.: Stages in Enzyme Adaptation. Adaptation in Microorganisms. III. Symp. of the Society f. General Microbiology, April 1953, London. S. 150. Cambridge: University Press 1953.

    Google Scholar 

  263. Pollock, M. R., et A. Toriani: Purification et caractéristiques physicochimiques de la penicillinase de Bacillus cereus. C. r. Acad. Sci Paris 237, 270 (1953).

    Google Scholar 

  264. Pollock, M. R., and C. J. Perret: Penicillinase adaptation and fixation of penicillin sulphur by Bacillus cereus spores. J. Gen. Microbiol. 8, 186 (1953).

    PubMed  CAS  Google Scholar 

  265. Pope, H.: The effect of benzoate and salicylate on the oxidative metabolism of tubercle bacilli. Amer. Rev. Tbc. 69, 705 (1954).

    CAS  Google Scholar 

  266. Pope, H., and D. T. Smith: Synthesis of B-complex vitamins by tubercle bacilli when grown on synthetic media. Amer. Rev. Tbc. 54, 559 (1946).

    CAS  Google Scholar 

  267. Proom, H.: Some observations on penicillinase. Brit. J. Exper. Path. 26, 98 (1945).

    CAS  Google Scholar 

  268. Rake, G., C. M. McKee, D. M. Hamre and C. L. Houck: Studies on Penicillin. II. Observations on Therapeutic Activity and Toxicity. J. of Immun. 48, 271 (1944).

    CAS  Google Scholar 

  269. Reid, R. D., L. C. Felton and M. A. Pittroff: Prolongation of the Penicillin-Activity with Penicillinase-subsisting Compounds. Proc. Soc. Exper. Biol. a. Med. 63, 438 (1946).

    CAS  Google Scholar 

  270. Ribeiro, L.: Sobre a produçâo duma substância inibidora da penicilina pelo bacilo Calmette-Guérin. J. Soc. cienc. med. Lisboa 119, 145 (1955).

    PubMed  CAS  Google Scholar 

  271. Richmond, L., and M. M. Cummings: An evaluation of methods of testing the virulence of acidfast bacilli. Amer. Rev. Tbc. 62, 632 (1950).

    CAS  Google Scholar 

  272. Rist, N., C. Libermann, F. Grumbach et J. C. Levaditi: Sur le pouvoir pathogène des bacilles tuberculeux isoniazido-résistants. Revue de la Tbc. 19, 659 (1955).

    CAS  Google Scholar 

  273. Rothe, W.: Wirksamkeitsbestimmung und Standardisierung der Penicillinase. Pharmazie 6, 15 (1951).

    PubMed  CAS  Google Scholar 

  274. Rothe, W.: Zur Kenntnis der Penicillinase. Pharmazie 5, 25 (1950).

    CAS  Google Scholar 

  275. Roulet, F., H. Wydler u. E. A. Zeller: Über die Enzyme des Mycobacterium tuberculosis und anderer säurefester Bakterien. II. Mitt. Über den enzymatischen Abbau von 1α-Oxysäuren durch säurefeste Bakterien. Helvet. chim. Acta 29, 1973 (1946).

    CAS  Google Scholar 

  276. Royce, A., C. Bowler and G. Sykes: The assay of penicillin using penicillinase. J. of Pharmacy a. Pharmacol. 4, 904 (1952).

    CAS  Google Scholar 

  277. Sasaki, K.: The enzymes of tubercle bacilli. Sei-I-Kai Med. J. 57, 2 (1938). Ref. Chem. Abstr. 35, 7448 (1941).

    CAS  Google Scholar 

  278. Saz, A. K., and F. Bernheim: The effect of benzoic acid and related compounds on the growth of certain mycobacteria. J. Bacter. 44, 385 (1942).

    CAS  Google Scholar 

  279. Saz, A. K., and F. Bernheim: The effect of 2,3,5-triiodobenzoate and various other compound on the growth of the tubercle bacillus. J. of Pharmacol. 73, 78 (1941).

    CAS  Google Scholar 

  280. Saz, A. K., F. R. Johnston, A. Burger and F. Bernheim: Effect of aromatic iodine compounds on the tubercle bacillus. Amer. Rev. Tbc. 48, 40 (1943).

    CAS  Google Scholar 

  281. Schaefer, W. B.: The effect of isoniazid on growing and resting tubercle bacilli. Amer. Rev. Tbc. 69, 125 (1954).

    CAS  Google Scholar 

  282. Schaefer, W. B.: The effect of ketone compounds on the inhibition of growth of tubercle bacilli by isoniazid in vitro. Amer. Rev. Tbc. 68, 273 (1953).

    CAS  Google Scholar 

  283. Schaefer, W. B., A. Marshak and B. Burkhart: The growth of Mycobacterium tuberculosis as a function of its nutrients. J. Bacter. 58, 549 (1949).

    CAS  Google Scholar 

  284. Schrödter, S.: Beobachtungen bei Anwendung des Neutralrot-Tests nach Dubos: Zbl. Bakter. 164, 120 (1955). Bericht über die 25. Tagg der Dtsch. Ges. für Hygiene u. Microbiologie 1955.

    Google Scholar 

  285. Segalove, M.: The Effect of Penicillin on Growth and Toxin Production by enterotoxic Staphylococci. J. Inf. Dis. 81, 228 (1947).

    CAS  Google Scholar 

  286. Singh, B., and D. A. Mitcheson: The bactericidal activities of combinations of Streptomycin, Isoniazid, p-Aminosalicylic acid (PAS), Oxytetracycline (Terramycin) and Viomycin against Mycobacterium tuberculosis. J. Gen. Microbiol. 13, 176 (1955).

    PubMed  CAS  Google Scholar 

  287. Singh, B., and D. A. Mitchison: Bactericidal activity of Streptomycin and Isoniazid in Combination with p-Aminosalicylic acid against Mycobacterium tuberculosis. J. Gen Microbiol. 12, 76 (1955).

    PubMed  CAS  Google Scholar 

  288. Smith, M. J. H.: The effects of salicylate and andreno-cortical preparations added in vitro upon the glycogen content of liver slices. Biochemic. J. 59, 52 (1955).

    CAS  Google Scholar 

  289. Smith, M. J. H., and S. W. Jeffrey: The effects of salicylate on oxygen consumption and carbohydrate metabolism in the isolated rat diaphragm. Biochemic. J. 63, 524 (1956).

    CAS  Google Scholar 

  290. Smith, M. J. H., and S. W. Jeffrey: Salicylate and Carbohydrate Metabolism. Nature (Lond.) 178, 310 (1956).

    CAS  Google Scholar 

  291. Smith, W., and M. M. Smith: Production of sterile and stable penicillinase. Lancet 1945, 809.

    Google Scholar 

  292. Sneath, P. H.: Proof of the spontaneity of a mutation to penicillinase production in Bacillus cereus. J. Gen. Microbiol. 13, 561 (1955).

    PubMed  CAS  Google Scholar 

  293. Snell, E. E., and L.D. Wright: A microbiological method for the determination of nicotinic acid. J. of Biol. Chem. 139, 675 (1941).

    CAS  Google Scholar 

  294. Soltys, M.: The effect of penicillin on mycobacteria in vitro and in vivo. Tubercle 33, 120 (1952).

    PubMed  CAS  Google Scholar 

  295. Spink, W. W., and V. Ferris: Penicillin resistant staphylococci: mechanisms involved in the development of resistance. J. Clin. Invest. 26, 379 (1947).

    PubMed  CAS  Google Scholar 

  296. Spink, W. W., and V. Ferris: Penicillin inhibitor from Staphylococcal which have developed resistance to Penicillin in the human body. Proc. Soc. Exper. Biol. a. Med. 59, 188 (1945).

    CAS  Google Scholar 

  297. Stapp, C.: Weitere Beiträge zur Kenntnis der Bakterienfermente. Über Katalase und Peroxydase bei Bakterien. Zbl. Bakter. 92, 161 (1924).

    CAS  Google Scholar 

  298. Stewart, G. T.: Studies on the effect of penicillin upon gram-negative bacteria. Penicillin-sulphonamide synergy. Z. Hyg. 45, 282 (1947).

    CAS  Google Scholar 

  299. Stur, D.: Der Bromkresolpurpurnährboden in der praktischen Typenbestimmung von Tuberkelbakterien. Acta path. (Københ.) 37, 279 (1955).

    CAS  Google Scholar 

  300. Tacking, R.: Penicillinase-producing bacteria in mixed infections in rabbits treated with penicillin 2. Studies on penicillinase-producing coli-and pyocyaneus bacteria. Acta path. scand. (Københ.) 35, 445 (1954).

    CAS  Google Scholar 

  301. Tacking, R.: Penicillinase-producing and penicillin-sensitive bacteria in two separate sites of infection in rabbits treated with penicillin. Acta path. scand. (Københ.) 36, 471 (1955).

    CAS  Google Scholar 

  302. Tacking, R.: Immunization experiments with penicillinase. Acta path. scand. (Københ.) 36, 61 (1955).

    CAS  Google Scholar 

  303. Tarshis, M. S., and A. W. Frisch: Chromogenic acid-fast bacilli from human sources. I. Cultural studies. Amer. Rev. Tbc. 65, 278 (1952).

    CAS  Google Scholar 

  304. Tarshis, M.S. and A. W. Frisch: Chromogenic acid-fast bacilli from human sources. II. Pathologic studies. Amer. Rev. Tbc. 65, 289 (1952).

    CAS  Google Scholar 

  305. Tarshis, M. S., W. A. Weed, M. V. Parker und W. B. Dunham: Chromogenic acid-fast bacilli from human sources. IV. In vitro response to a number of antimicrobial agents on glycerol-blood agar medium. Amer. Rev. Tbc. 72, 119 (1955).

    CAS  Google Scholar 

  306. Tarshis, M. S.: Chromogenic acid-fast bacilli from human sources. Amer. Rev. Tbc. 73, 601 (1956).

    Google Scholar 

  307. Tarshis, M. S., and A. W. Frisch: Blood media for the cultivation of Mycobacterium tuberculosis. Amer. J. Clin. Path. 21, 101 (1951).

    CAS  Google Scholar 

  308. Tarshis, M. S., W. A. Weed, P. C. Kinsella, M. V. Parker and W. B. Dunham: Further experience with a new blood medium for the cultivation of Mycobacterium tuberculosis. Amer. J. Publ. Health 45, 1157 (1955).

    CAS  Google Scholar 

  309. Taubeneck, U.: Die Penicillininaktivierung durch Proteus-Arten. Zbl. Bakter. I Orig. 167, 345 (1956).

    CAS  Google Scholar 

  310. Taubeneck, U.: Über die Inaktivierung von Penicillin durch Proteus vulgaris. Arch. Mikrobiol. 24, 423 (1956).

    PubMed  CAS  Google Scholar 

  311. Thrap-Meyer, H.: Generalized BCG infection in man. I. Clinical report. Acta tbc. scand. (Københ.) 29, 173 (1954).

    Google Scholar 

  312. Timpe, A., and E. H. Runyon: The relationship of „atypical“ acid-fast bacteria to human disease. J. Labor. a. Clin. Med. 44, 202 (1954).

    CAS  Google Scholar 

  313. Tirunarayanan, M. O., u. W. A. Vischer: Effect of Isoniazid on Catalase and Peroxidase of Tubercle Bacilli in vitro. Naturwiss. 43, 474 (1956).

    CAS  Google Scholar 

  314. Treffers, H. P.: Studies on resistance to antibiotics. I. The action of penicillin on some gram-positive and gram-negative organisms and its potentiation by various inhibitors. Yale J. Biol. a. Med. 18, 609 (1946).

    CAS  Google Scholar 

  315. Tschesche, R., F. Korte u. J. Bethge: Über die Rolle des Wasserstoffperoxyds bei der Inhibition nach Dold. III. Die quantitative Bestimmung des Wasserstoffperoxyds im Speichel. Wasserstoffperoxyd als Ursache der Hemmung des Bakterienwachstums. Z. Naturforsch. 6b, 22 (1951).

    CAS  Google Scholar 

  316. Tunevall, G.: Penicillinasbildande stafylokocker som hinder för penicillinbehandlingens effekt vid scarlatina. (Penicillinase-producing micrococci reducing the effectivity of penicillin in scarlet fever). Sv. Läkartidn. 52, 2197 (1955).

    CAS  Google Scholar 

  317. Uecker, W.: Enzyme der Mykobakterien. I. Mitt. Die Hydroperoxydasen. Zbl. Bakter. I Orig. 164, 424 (1955).

    CAS  Google Scholar 

  318. Ungar, J.: Penicillinase from B. subtilis. Nature (Lond.) 154, 236 (1944).

    CAS  Google Scholar 

  319. Van Deinse, F.: Quelques reflexions au sujet de quatre décès dus aparemment à la vaccination BCG. Kev. Tbc. 20, 44 (1956).

    Google Scholar 

  320. Viallier, J., J. Kalb und J. Tibaud: Sur la coloration par le rouge neutre du bacille tuberculeux. C. r. Soc. Biol. Paris 144, 1513 (1950).

    PubMed  CAS  Google Scholar 

  321. Viallier, J., et J. Tigaud: La réaction de Dubos et Middlebrook; test cyto-chimique de la virulence des Mycobactéries. Ann. Inst. Pasteur 85, 746 (1953).

    CAS  Google Scholar 

  322. Virtanen, A. J., u. H. Karström: Quantitative Enzymbestimmungen an Microorganismen. I. Der Katalasegehalt der Bakterien. Biochem. Z. 161, 9 (1925).

    CAS  Google Scholar 

  323. Waaler, E., and P. Oeding: Generalized BCG infection in man. III. Autopsy findings. Acta tbc. scand. (Københ.) 29, 188 (1954).

    Google Scholar 

  324. Wagener, K., u. E. Mitscherlich: Zwei neue Nährböden zur kulturellen Differenzierung der Tuberkelbakterientypen. Tuberkulosearzt 5, 274 (1951).

    PubMed  CAS  Google Scholar 

  325. Wagner, W.-H.: Über den hemmenden Einfluß von Aureomycin auf den oxydativen Abbau aromatischer Substanzen durch saprophytäre Mycobakterien. Naturwiss. 37, 525 (1950).

    CAS  Google Scholar 

  326. Wagner, W.-H.: Über den atmungssteigernden Einfluß von o-Chlorbenzoesäure bei Mykobakterien. Naturwiss. 37, 92 (1950).

    CAS  Google Scholar 

  327. Wagner, W.-H.: Oxydativer Abbau aromatischer Verbindungen durch Bakterien. Angew. Chem. 63, 28 (1951).

    Google Scholar 

  328. Wagner, W.-H.: Über den oxydativen Abbau aromatischer Substanzen durch saprophytäre Mycobakterien. Biochem. Z. 322, 121 (1951).

    PubMed  CAS  Google Scholar 

  329. Waisman, H. A., and C. A. Elvehjem: Chemical and vitamin B6. Industr. Engin. Chem. 13, 221 (1941).

    CAS  Google Scholar 

  330. Wallmark, G.: Bacteriophage types, sensitivity to antibiotics, and penicillinase production of Staphylococcus aureus (pyogenes); a survey. Acta Soc. Med. Upsaliensis 59, 209 (1954).

    CAS  Google Scholar 

  331. Wallmark, G.: The production of penicillinase in Staphylococcus pyogenes and its relation to penicillin resistance. Acta path. scand. (Københ.) 34, 182 (1954).

    CAS  Google Scholar 

  332. Wallmark, G.: In vitro induced resistance to penicillin, streptomycin, and aureomycin in penicillin-sensitive and in penicillinase producing Staphylococcus aureus pyogenes. Acta path. scand. (Københ.) 34, 191 (1954).

    CAS  Google Scholar 

  333. Welsch, M.: Quelques propriétés de la pénicillinase de Bacillus subtilis. C. r. Soc. Biol. Paris 141, 852 (1947).

    Google Scholar 

  334. Wilder Smith, A. E.: The action of phosgene on acid hydrazides to give 1,3,4-oxdiazolones of interest in the treatment of tuberculosis. Science (Lancaster, Pa.) 119, 514 (1954).

    Google Scholar 

  335. Wilson, F. J., C. Kalish and C. H. Fish: Use of oxidation-reduction dyes in the determination of virulence of mycobacteria in vitro. Amer. Rev. Tbc. 65, 187 (1952).

    CAS  Google Scholar 

  336. Wise, W. S., and G. H. Twigg: The determination of penicillinase activity. Analyst (Lond.) 75, 106 (1950).

    CAS  Google Scholar 

  337. Wolinsky, E., M. M. Smith and W. Steenken, Jr.: Isoniazid susceptibility, catalase activity, and guinea pig virulence of recently isolated cultures of tubercle bacilli. Amer. Rev. Tbc. 73, 768 (1956).

    CAS  Google Scholar 

  338. Wood, L. E., V. B. Buhler and A. Pollak: Human infection with the „yellow“ acid-fast bacillus. Amer. Rev. Tbc. 73, 917 (1956).

    CAS  Google Scholar 

  339. Woodruff, H. B., and J. W. Foster: Microbiological aspects of penicillin. VII. Bacterial penicillinase. J. Bacter. 49, 7 (1945).

    CAS  Google Scholar 

  340. Wrinkle, C. K., and R. A. Patnode: A test tube modification of the oxidation-reduction dye test for the determination of virulence of mycobacteria in vitro. Amer. Rev. Tbc. 66, 99 (1952).

    CAS  Google Scholar 

  341. Wylie, J. A. H., and E. Vincent: The sensitivity of organisms of the genus Leptospira to penicillin and streptomycin. J. of Path. 59, 247 (1947).

    CAS  Google Scholar 

  342. Yegian, D., and V. Budd: Certain nonpathogenic mycobacteria as a source of error in diagnosis and drug-susceptibility tests. Amer. Rev. Tbc. 68, 557 (1953).

    CAS  Google Scholar 

  343. Zeller, E. A. and Ch. A. Owen: Enzymology of the Genus Mycobacterium. Fortschr. Tbk.forsch. 4, 39 (1951).

    Google Scholar 

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  1. Rudolf Bönicke
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Bönicke, R. (1957). Vergleichende Untersuchungen über den Stoffwechsel der verschiedenen Arten und Varianten der Gattung Mycobacterium. In: Freerksen, E. (eds) Jahresbericht Borstel. Tuberkulose-Forschungsinstitut Borstel, vol 1956/57. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-30612-3_2

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