Microscopic observations of the mesenteric circulation in rabbits subjected to reversible and irreversible haemorrhagic shock
The changes occurring in the peripheral circulation in severe shock have been described by Chambers and Zweifach and their associates in terms of a progressive loss of tone in the peripheral vessels, especially of the splanchnic area, beginning with a reduction in “vasomotion” and eventually terminating in paralysis affecting most intensely the precapillary sphincters and venules. This description is based mainly on microscopic observations in vivo of the exteriorised mesentery of dogs and rats subjected to haemorrhagic shock (1–2). We report here similar experiments performed on rabbits put into shock by the elevated reservoir technique.
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