Bone Cells and Structure of Cancellous Bone in Primary Hyperparathyroidism — A Histomorphometric and Electron Microscopic Study

  • G. Delling
  • R. Ziegler
  • A. Schulz


Primary hyperparathyroidism is more often found without any clinical important bone disease due to radioimmunological determination of serum parathyroid hormone and automatic screening of serum calcium (14). Morphological bone changes of these so-called mild forms of primary hyperparathyroidism were published by a few research groups only (1, 8, 10, 12). Periods of vitamin D defiency were discussed as a pathogenic factor for the development of parathyroid adenomas (16, 8). Increased parathyroid hormone secretion influences bone cells and vitamin D metabolism. In primary hyperparathyroidism, changes of bone formation and mineralization can be expected in addition to increased bone resorption.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1976

Authors and Affiliations

  • G. Delling
    • 1
    • 2
  • R. Ziegler
    • 1
    • 2
  • A. Schulz
    • 1
    • 2
  1. 1.Institute of PathologyUniversity of Hamburg and Centre of Internal Medicine and PediatricsGermany
  2. 2.Department of Endocrinology and MetabolismUniversity of UlmGermany

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