Abstract
In recent years, there have been intensive efforts by several laboratories to elucidate various aspects of the parameters involved in the regulation of calcium and phosphorus metabolism. Three of the most important of these biological regulators are the seco steroid, calciferol (vitamin D), parathyroid hormone, and calcitonin. With each of these regulators, outstanding developments and advances have been made in recent years. It is the purpose of this article to briefly outline some of the developments that have occurred specifically with regard to our understanding of the shape or chemical conformation of vitamin D, its subsequent metabolism by the kidney in a regulated fashion, the interaction of the product steroid hormone (1,25-dihydroxycholecalciferol) with both the intestinal mucosal system where it mediates calcium absorption, and with the parathyroid gland. We have reviewed this subject in depth previously (2, 6).
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References
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Norman, A.W. et al. (1976). Current Concepts of the Chemical Conformation, Metabolism, and Interaction of the Steroid, Vitamin D, with the Endocrine System for Calcium Homeostasis. In: Nielsen, S.P., Hjørting-Hansen, E. (eds) Calcified Tissues 1975. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-29272-3_23
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DOI: https://doi.org/10.1007/978-3-662-29272-3_23
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