Immunological Investigations in Myasthenia Gravis and Other Skeletal Muscle Disorders

  • D. Ricken
Part of the Bayer-Symposium book series (BAYER-SYMP, volume 1)

Abstract

Since many years it has been looked for immune phenomena in skeletal muscle disorders. If positive findings were reported they referred to humoral antibodies or factors. Cellular immunity has not been investigated yet. However,
Table 1

Immune phenomena in skeletal muscle disorders

 

Humoral antibodies against Striated muscle

 

Striated muscle

Smooth muscle

Epithrloid thymus cells

Nerve

Other immunephenomena

Thymoma thymushyperplasia

Musclefibre destruction

Myasthenia gravis

+

ø

+

(+)

ANF, LE RF, ATh

+

((+))

Muscular dystrophy

ø

ø

ø

ø

ø

ø

+++

Polymyositis

ø

ø

ø

n.d.

RF

((+))

+++

Dermatomyositis

ø

ø

ø

n.d.

RF, ANF LE

((+))

++

Other skeletal muscle disorders

ø

ø

ø

n.d.

ø

ø

ø

ATh = Antithyroglobulin.

n.d. = not done.

there is the occurence of thymoma or hyperplastic thymus particularly in myasthenia gravis which perhaps represents a condition of cellular immunity.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1969

Authors and Affiliations

  • D. Ricken
    • 1
  1. 1.Medizinische Universitätsklinik für Innere- und Nervenkrankheiten53 Bonn, VenusbergGermany

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