Abstract
The activation of DNA- and RNA-metabolism in transforming lymphocytes is accompanied by an increase of the whole metabolism of the cell; especially the activity of the glycolytic and oxydative enzymes is enhanced [1, 2, 4, 5]. Morphologically
Table 1. Mean values of transformed lymphocytes in cultures with (P-culture) and without added phytohemagglutinin (N-culture) counted 24 to 96 h after onset of cell Culturing
Hours from start of culture | Average percentage of cells transformed | |
N-cultures% | P-cultures% | |
24 | less than 3.00 | less than 3.00 |
48 | 4.87 | 15.67 |
72 | 4.82 | 20.00 |
96 | 3.55 | 19.12 |
a higher number of mitochondria in the lymphocyte corresponds to this findings [1, 2]. In our investigations the O2-uptake of transformed lymphocytes was measured in daily intervals after addition of the stimulating agent.
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Warnatz, H. (1969). Results of Some Investigations on Lymphocyte Transformation in vitro. In: Westphal, O., Bock, HE., Grundmann, E. (eds) Current Problems in Immunology. Bayer-Symposium, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-29237-2_13
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