The Role of Placenta in the Synthesis and Metabolism of Proteins

  • John B. Josimovich


The main goal of this review of placental protein metabolism in the primate is to present certain areas of information which, although limited, might serve as a basis for future techniques of diagnosis and therapy of disordered fetal functions. Since our state of knowledge even in narrowly defined areas is quite incomplete, it is hoped that this discussion will designate where more data is readily accessible to newer research techniques. Figure 1 summarizes the five ways in which the primate chorioallantoic placenta affects protein metabolism: synthesis of structural and enzymatic proteins which remain within the placenta, synthesis of protein hormones, transplacental passage of proteins and amino acids, storage, and degradation of proteins.


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© Springer Science+Business Media New York 1968

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  • John B. Josimovich

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