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Prevention of Rh Disease with Passive Rh-Immunoglobulin

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Diagnosis and Treatment of Fetal Disorders

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Abstract

The discovery of the pathogenesis of hemolytic disease of the newborn by P. Levine (1939) and the simultaneous and related discovery of the Rh factor in 1940 by K. Landsteiner and A. S. Wiener (1940) together constitute one of the scientific milestones of this century.

Supported in part by grants U-1307 from The Health Research Council City of New York and by National Institutes of Health Grant HD00721.

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References

  • Clarke, C. A., W. T. A. Donohoe, R. B. McConnell, J. C. Woodrow, R. Finn, J. R. Krevans, W. Kulke, D. Lehane, and P. M. Sheppard. Further experimental studies on the prevention of Rh hemolytic disease. Brit. Med. J. 1: 979, 1963.

    Article  CAS  Google Scholar 

  • Clarke, C. A., and P. M. Sheppard. Prevention of rhesus haemolytic disease The Lancet, August 14, p. 343, 1965.

    Google Scholar 

  • Clarke, C. A., R. Finn, D. Lehane, R. B. McConnell, P. M. Sheppard, and J. C. Woodrow. Dose of anti-D gamma globulin in prevention of Rh-haemolytic disease of the newborn. Brit. Med. J. 1: 213, 1966.

    Article  CAS  Google Scholar 

  • Clarke, C. A., and R. Finn. Personal communication.

    Google Scholar 

  • Cohen, C., and W. H. Allton, Jr. Isoimmunization in the rabbit with antibodycoated erythrocytes. Nature 193: 990, 1962.

    Article  PubMed  CAS  Google Scholar 

  • Finn, R., C. A. Clarke, W. T. A. Donohoe, R. B. McConnell, P. M. Sheppard, D. Lehane, and W. Kulke. Experimental studies on the prevention of Rh hemolytic disease. Brit. Med. J. 1: 1486–1490, 1961.

    Article  CAS  Google Scholar 

  • Finn, R., C. A. Clarke, R. B. McConnell, and J. C. Woodrow. Response to an article by Cohen and Allton. Nature 193: 991, 1962.

    Article  Google Scholar 

  • Finn, R., D. T. Harper, S. A. Stallings, and J. R. Krevans. Transplacental hemorrhage. Transfusion 3: 114, 1963.

    Article  Google Scholar 

  • Finn, R. Personal communication.

    Google Scholar 

  • Freda, V. J., and J. G. Gorman. Third Combined Annual Report of The Columbia-Presbyterian Medical Center, New York, N.Y., p. 84, 1961.

    Google Scholar 

  • Freda, V. J., and J. G. Gorman. Antepartum management of Rh hemolytic disease. Bull. Sloane Hosp. Worn. 8: 147–158, 1962.

    CAS  Google Scholar 

  • Freda, V. J. Placental transfer of antibodies in man. Amer. J. Obst. Gynec. 84: 1756, 1962.

    Google Scholar 

  • Freda, V. J., J. G. Gorman, and W. Pollack. Successful prevention of sensitization to Rh with an experimental anti-Rh gamma2 globulin antibody preparation. Fed. Proc. 22: 374, 1963.

    Google Scholar 

  • Freda, V. J., J. G. Gorman, Successful prevention of experimental Rh sensitization in man with an anti-Rh gamma2 globulin antibody preparation (a preliminary report). Transfusion 4: 26–32, 1964.

    Article  PubMed  CAS  Google Scholar 

  • Freda, V. J., J. G. Robertson, and J. G. Gorman. Antepartum management and prevention of Rh isoimmunization. Ann. N.Y. Acad. Sciences 127: 909–925, 1965.

    Article  Google Scholar 

  • Freda, V. J., J. G. Gorman, and W. Pollack. Prevention of Rhesus hemolytic disease. The Lancet, p. 690, Oct. 2, 1965.

    Google Scholar 

  • Freda, V. J., Rh factor—prevention of isoimmunization and clinical trial on mothers. Science 151: 828, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Freda, V. J., Unpublished data.

    Google Scholar 

  • Freda, V. J. Antepartum management of the Rh problem. Progress In Hematology, Vol. V, 1966 (in press).

    Google Scholar 

  • Gorman, J. G., V. J. Freda, and W. Pollack. Intramuscular injection of a new experimental gamma2 globulin preparation containing high levels of anti-Rh antibody as a means of preventing sensitization to Rh. Proceedings of the IX Congress of International Society of Hematology 2: 545–549, 1962.

    Google Scholar 

  • Gorman, J. G., Prevention of sensitization to Rh with anti-Rh gamma globulin. Federa- tion Proceedings 23: 238, 1964.

    Google Scholar 

  • Gorman, J. G., Prevention of iso-immunization to the Rh factor using high titer anti-Rh gamma globulin. Proceedings X Congress International Society Blood Transfusion, Stockholm, pp. 949–955, 1964.

    Google Scholar 

  • Gorman, J. G., Prevention of Rhesus haemolytic disease. The Lancet, July 24, p. 181, 1965.

    Google Scholar 

  • Gorman, J. G. Prevention of immunization to the Rh factor. The Jewish Memorial Hospital Bulletin 10: 142, 1965.

    Google Scholar 

  • Gorman, J. G., V. J. Freda, W. Pollack, and J. G. Robertson. Protection from immunization in Rh incompatible pregnancies: a progress report. Bulletin of the New York Academy of Medicine 42: 458, 1966.

    PubMed  CAS  Google Scholar 

  • Hamilton, E. Personal communication.

    Google Scholar 

  • Jennings, E. R., and J. F. Sullivan. Personal communication.

    Google Scholar 

  • Kleihauer, E., H. Braun, and K. Betke. Demonstration von Fetalem Hamoglobin in den erythrocyten eines blutausstrichs, Klin. Wschr. 35: 637–638, 1957.

    Article  PubMed  CAS  Google Scholar 

  • Krevans, J., and A. Montague. Medical World News, Vol. 6, No. 36, p. 32, 1965.

    Google Scholar 

  • Landsteiner, K., and A. S. Wiener. An agglutinable factor in human blood recognized by immune sera for Rhesus blood. Proc. So. Exp. Biol. N.Y. 43: 223, 1940.

    CAS  Google Scholar 

  • Levine, P., and R. E. Stetson. An unusual case of intragroup agglutination. J. Amer. Med. Assn. 113: 126–127, 1939.

    Article  Google Scholar 

  • Levine, P., E. M. Katzin, and L. Burnham. Isoimmunization in pregnancy: its possible bearing on the etiology of erythroblastosis foetalis, J.A.M.A. 116: 825, 1941.

    Article  Google Scholar 

  • Levine, P., Serological factors as possible cause in spontaneous abortions. J. Hered. 34: 71, 1943.

    CAS  Google Scholar 

  • Levine, P., The influence of the ABO system on Rh hemolytic disease. Hum. Biol. 30: 14, 1958.

    PubMed  CAS  Google Scholar 

  • McConnell, R. B. The prevention of Rh haemolytic disease. Ann. Rev. Med. 17: 291, 1966.

    Article  PubMed  CAS  Google Scholar 

  • Nevanlinna, H. R. Factors affecting maternal Rh immunization. Ann. Med. Exp. Fenn. Supp. 2, Vol. 31, 1953.

    Google Scholar 

  • Robertson, J. G., V. J. Freda, W. Pollack, and J. G. Gorman. Prevention of immunization to Rh with anti-Rh gamma globulin. Fed. Proc. 24: 696, 1965.

    Google Scholar 

  • Schneider, J., and O. Preisler. Untersuchungen zur serologischen Prophylaxe der Rh-Sensibilisierung. Blut 12: 4, 1965.

    Article  PubMed  CAS  Google Scholar 

  • Schneider, J., and O. Preisler. Personal communication.

    Google Scholar 

  • Smith, T. Active immunity produced by so-called balanced or neutral mixtures of diphtheria toxin and antitoxin. J. Exp. Med. 11: 241, 1909.

    Article  Google Scholar 

  • Stern, K., I. Davidson, and L. Masaitis. Experimental studies on Rh immunization. Am. J. Clin. Path. 26: 833, 1956.

    Google Scholar 

  • Stern, K., H. S. Goodman, and M. Berger. Experimental isoimmunization to hemoantigens in man. J. Immun. 87: 189, 1961.

    CAS  Google Scholar 

  • Woodrow, J. C., C. A. Clarke, W. T. A. Donohoe, R. Finn, R. B. McConnell, P. M. Sheppard, D. Lehane, S. H. Russell, W. Kulke, and M. Durkin. Prevention of Rh-haemolytic disease: a third report. Brit. M. J. 1: 279–283, 1965.

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. Vincent J. Freda
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Editors and Affiliations

  1. Columbia University, USA

    Karlis Adamsons M.D., Ph.D. (Chairman, Associate Professor of Obstetrics and Gynecology) (Chairman, Associate Professor of Obstetrics and Gynecology)

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© 1968 Springer Science+Business Media New York

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Freda, V.J. (1968). Prevention of Rh Disease with Passive Rh-Immunoglobulin. In: Adamsons, K. (eds) Diagnosis and Treatment of Fetal Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-26381-5_21

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  • DOI: https://doi.org/10.1007/978-3-662-26381-5_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-24268-1

  • Online ISBN: 978-3-662-26381-5

  • eBook Packages: Springer Book Archive

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