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Peliosis Hepatis, Rodents

  • Chapter
Digestive System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY,volume 3))

Abstract

Macroscopically, peliosis hepatis is best visible at the surface of the liver. The lesion is seen as blood-filled, thin-walled cavities projecting above the liver surface (Fig. 127). The blood-filled spaces stand out clearly as dark areas against the otherwise brown liver tissue. Large peliotic lesions may also be identified at the cut surface. Frequently, however, it is extremely difficult or even impossible to detect peliosis with the naked eye after the animal has died spontaneously under conditions with a weak blood supply to the liver. When the liver is removed from anesthetized animals after laparotomy, peliosis is readily visible only as long as the liver is connected with the blood circulation, but usually becomes invisible when the blood is lost during removal of the organ.

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Authors
  1. Peter Bannasch
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  2. Klaus Wayss
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  3. Heide Zerban
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Editor information

Editors and Affiliations

  1. ILSI Research Foundation, Harvard Medical School, 1126 Sixteenth Street. N.W., Washington, DC, 20036, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) (Professor of Comparative Pathology, Emeritus)

  2. Sanofi Winthrop, Toxicology U.S., Nine Great Valley Parkway, Malvern, PA, 19355, USA

    James A. Popp D.V.M., Ph.D. (International Director of Toxicology, Vice President) (International Director of Toxicology, Vice President)

  3. Medizinische Hochschule Hannover, Institut für Experimentelle Pathologie, Konstanty-Gutschow-Strasse 8, 30625, Hannover, Germany

    Ulrich Mohr M.D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1997 Springer-Verlag Berlin Heidelberg

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Bannasch, P., Wayss, K., Zerban, H. (1997). Peliosis Hepatis, Rodents. In: Jones, T.C., Popp, J.A., Mohr, U. (eds) Digestive System. Monographs on Pathology of Laboratory Animals, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-25996-2_20

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  • DOI: https://doi.org/10.1007/978-3-662-25996-2_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-0-944398-75-3

  • Online ISBN: 978-3-662-25996-2

  • eBook Packages: Springer Book Archive

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