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Some Aspects of the Functional Polarity of Epithelia

  • V. Capraro

Abstract

Functional polarity is a property inherent in all epithelial cells. This property seems to be related, in some cases, only to the physical and/or chemical structure of the membranes covering the two cellular poles without being affected by their metabolism. Lactic acid, water soluble, ionizing substance, accumulates in several epithelia and diffuses through the basal and luminal membranes into the surrounding media (Wilson 1954, Pfleger et al. 1958, Leaf 1959, Hogben 1962); the effluxes, however, are not the same on both sides, being higher through the basal than through the luminal membrane. A difference between the permeability constants of the two cellular membranes (Leaf 1959) seems to account for the observed ratio between the serosal and mucosal lactic acid fluxes.

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References

  1. Andersen, B., and H. H. Ussing, 1957: Acta Physiol. Scand. 39, 228.CrossRefGoogle Scholar
  2. Capraro, V., E. Milla, and A. Bianchi, 1963: Nature 199, 1099.CrossRefGoogle Scholar
  3. V., E. Mill a,A. Bianchi, and C. Lipp e, 1963: Experientia 19, 347.CrossRefGoogle Scholar
  4. Cohen, L L, and K. C. Huang, 1964: Amer. J. Physiel. 206, 647.Google Scholar
  5. Crane, R. K., 1962: Fed. Proc. 21, 891.Google Scholar
  6. Cremaschi, D., C. Lippe, and V. Capraro, 1965: Boll. Soc. It. Biol. Sper. 41, 171.Google Scholar
  7. Csaky, T. Z., and M. Thale, 1960: J. Physiol. 151, 59.Google Scholar
  8. Csaky, T. Z., and M. Thale,1961: Amer. J. Physiol. 201, 999.Google Scholar
  9. Curran, P. F., F. C. Herrera, and W. J. Flanigan, 1963: J. Gen. Physiol. 46. 1011.CrossRefGoogle Scholar
  10. Esposito, G., A. Faelli, and V. Capraro, 1964: Experientia 20, 122.CrossRefGoogle Scholar
  11. Finch, L. R., and J. R. Hird, 1960: Biochim. Biophys. Acta 43, 278.CrossRefGoogle Scholar
  12. Fisher, R. B., and D. S. Parsons, 1953: J. Physiol. 119, 210.Google Scholar
  13. Frazier, H. S., E. F. Dempsey, and A. Leaf, 1962: J. Gen. Physiol, 45, 529.CrossRefGoogle Scholar
  14. Gilles Baillien, M., and E. Schoffeniels, 1965: Arch. Int. Physiol. 73, 355.CrossRefGoogle Scholar
  15. Hakim, A. A., and N. Lifson, 1964: Amer. J. Physiol. 206, 1315.Google Scholar
  16. IIarrison, H. E., and C. Harrison, 1963: Amer. J. Physiol. 205, 107.Google Scholar
  17. IIogben, C. A. M., 1962: Circulation 24, 1179.Google Scholar
  18. Jeris, E. L., and D. H. Syth. 1959: J. Physiol. 149, 433.Google Scholar
  19. Leaf, A., 1959: J. Cell. Conip. Physiol. 54, 103.CrossRefGoogle Scholar
  20. Leaf, A., and R. M. Hays, 1962: J. Gen. Physiol. 45, 221.CrossRefGoogle Scholar
  21. Lippe. C.. A. Bianchi, D. Cremaschi. and V. Capraro, 1965: Arch. Tnt. Phvsiol. 73, 43.CrossRefGoogle Scholar
  22. Pfleger, K., II. Jacobi, and W. Runime, 1958: Naunyn-Schmiedebergs Arch. Exper. Path. u. Pharmak. 234, 400.Google Scholar
  23. Samiy, A. H.. and R. P. Spencer, 1961: Amer. J. Physiol. 200, 505.Google Scholar
  24. Schuttz. S. G., and R. Zalusky, 1964: J. Gen. Physiol. 4?, 1043.Google Scholar
  25. Wiison, T. H., 1954: Biochem. J. 56, 521.Google Scholar

Copyright information

© Springer-Verlag Wien 1967

Authors and Affiliations

  • V. Capraro
    • 1
  1. 1.Institute of General PhysiologyMilanItaly

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