Some Aspects of the Functional Polarity of Epithelia

  • V. Capraro


Functional polarity is a property inherent in all epithelial cells. This property seems to be related, in some cases, only to the physical and/or chemical structure of the membranes covering the two cellular poles without being affected by their metabolism. Lactic acid, water soluble, ionizing substance, accumulates in several epithelia and diffuses through the basal and luminal membranes into the surrounding media (Wilson 1954, Pfleger et al. 1958, Leaf 1959, Hogben 1962); the effluxes, however, are not the same on both sides, being higher through the basal than through the luminal membrane. A difference between the permeability constants of the two cellular membranes (Leaf 1959) seems to account for the observed ratio between the serosal and mucosal lactic acid fluxes.


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Copyright information

© Springer-Verlag Wien 1967

Authors and Affiliations

  • V. Capraro
    • 1
  1. 1.Institute of General PhysiologyMilanItaly

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