Abstract
In 1953 it became clear from work with human red cells that the K-loss from cells treated with cardiac glycosides (or their aglucones) is due to inhibition of active Na-K-transport [1]. The inhibition of the Na-pump was later demonstrated in most cells showing active Na-K-transport, ranging from the frog skin epithelium to the cells of the ciliary body of the human eye [2–14].
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References
Schatzmann, H. J., 1953: Hely. Physiol. Acta 11, 346.
Glynn, I. M., 1957: J. Physiol. 136, 148.
Kahn, J. B., jr., 1961: Proc. 1st Intern. Pharmacol. Meeting, vol. III, p. 111.
Johnson, J. A., 1956: Amer. J. Physiol. 187, 328
Sehreiber, S., 1956: Amer. J. Physiol. 185, 337.
Koefoed-Johnson, J. V., 1957: Acta Physiol. Scand. 42, Suppl. 145.
Caldwell, P. C., and R. D. Keynes, 1959: J. Physiol. 148, 8 P.
Orloff, J., and M. Burg, 1960: Amer. J. Physiol. 199, 49.
Wilde, W. S., and P. J. Howard, 1960: J. Pharm. Exper. Ther. 130, 232.
Horowicz, P., and C. J. Gerber, 1965: J. Gen. Physiol, 48, 489.
Kleinzeller, A., and A. Knotkova, 1964: J. Physiol. 175, 172.
Simon, K. A., and S. L. Bonting, 1962: A. M. A. Arch. Ophthalm. 68,22.
Daniel, E. E., and K. Rob-Robinson, 1966: J. Physiol. 154, 445.
Kao, C. Y., and D. Zakim, 1962: J. Gen. Physiol, 45, 606 A.
Whittam, R., 1958: J. Physiol. 140, 479.
Sen, A. K., and R. L. Post, 1964: J. Biol. Chem. 239, 345.
Skou, J. C., 1957: Biochim. Biophys. Acta 23, 394.
Repke, K., 1964: Arzneimittelforsch. 14, 1073.
Dransfeld, H., and K. Greeff, 1964: Arch. Exper. Path. Pharm. 249, 425.
Kahn, J. B., jr., 1962: Proc. Soc. Exper. Biol. Med. 110, 412.
Gallois, and Hardy, 1876: J. de Pharmacie et de Chimie 24, 25.
Harnack, E., and R. Zabrocki, 1882: Arch. Exper. Path. Pharm. 15, 403.
Santi, R., 1939: Arch. Exper. Path. Pharm. 193, 152.
Maling, H. M., and O. Krayer, 1946: J. Pharmacol, Exper. Ther. 86, 66.
Kroneberg, G., K. H. Meyer, E. Schraufstätter, S. Schütz, and K. Stoepel, 1964: Naturwissenschaften 51, 192.
Kroneberg, G., and K. Stoepel, 1964: Arch. Exper, Path. Pharm. 249, 393.
Greeff, K., K. Meng, and D. Schwarzmann, 1964: Arch. Exper. Path. Pharm. 249, 416.
Glynn, I. M., 1962: J. Physiol. 160, 18 P.
Whittam, R., 1962: Biochem. J. 84, 110.
Whittam, R., M. Ager, 1962: Biochim. Biophys. Acta 65, 383.
Post, R. L., C. R. Merritt, C. R. Kinsolving, and C. D. Albright, 1960: J. Biol. Chem. 235, 1796.
Dunham, E. T., and I. M. Glynn, 1961: J. Physiol. 156, 274.
Post, R. L., A. K. Sen, and A. S. Rosenthal, 1965: J. Biel. Chem. 240, 1437.
Hokin, M. R., and L. E. Hokin, 1961: Lab. Invest. 10, 1151.
Judah, J. D., and K. Ahmed, 1964: Biol. Rev. 39, 160.
Whittam, R., and K. P. Wheeler, 1961: Biochim. Biophys. Acta 51, 622.
Repke, K., and H. J. Portius, 1963: Experientia 19, 452.
Schatzmann, H., 1965: Biochim. Biophys. Acta 94, 89.
Schatzmann, H., 1964: Experientia 20, 551.
Schatzmann, H., 1963: Hely.,Physiol. Acta 21, C 60.
Straub, F. B., 1954: Acta Physiol. Acad. Sci. Hung. 4, 235.
Schatzmann, H., and B. Raess, 1965: Hely. Physiol, Acta 22, C 47.
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Schatzmann, H.J. (1967). Effect of Cardiac Glycosides on Active Na-K-Transport. In: Bolis, L., Capraro, V., Porter, K.R., Robertson, J.D. (eds) Symposium on Biophysics and Physiology of Biological Transport. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-25134-8_32
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DOI: https://doi.org/10.1007/978-3-662-25134-8_32
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