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Effect of 5-Hydroxytryptamine on Sodium Transport across Bullfrog Skin

  • Charles V. Paganelli
  • Suk Ki Hong

Abstract

5-hydroxytryptamine (5 HT) has been shown to promote the reabsorption of sodium by the renal tubule (Blackmore 1958, Little et al. 1961); it is also considered as an inhibitory transmitter substance in the central nervous system (Brodie and Shaw 1957, Twarog 1954). Despite these and other important rôles played by 5 HT, its effect on membrane permeability and transport in relatively well-defined systems is not known. Hence, this investigation was undertaken to study the effect of 5 HT on sodium transport across frog skin.

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References

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Copyright information

© Springer-Verlag Wien 1967

Authors and Affiliations

  • Charles V. Paganelli
    • 1
  • Suk Ki Hong
    • 1
  1. 1.Department of PhysiologyState University of New York at BuffaloBuffalo 14USA

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