Advertisement

Energy Metabolism and Ion Transport Studied in Single Neurons

  • Ezio Giacobini

Abstract

The stretch receptor organ of crustaceans allows us to work with a whole, intact and isolated neuron which can be kept in apparently normal functional condition for several hours and in which impulse activity as well as oxygen uptake (Giacobini 1963 and 1965 a), enzymatic activity, substrates and ion concentrations (Giacobini 1965 a, Giacobini and Grasso 1966, Giacobini -and Marchisio 1966a, Giacobini and Kar1sson 1965, Giacobini 1965 b) can be studied 1. The increase in oxygen uptake which follows impulse activity is a function of the impulse frequency and is not dependent on the external K+ and Ca++ concentrations (Giacobini 1965a, Giacobini et al. 1965).

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Edwards, C., C. Terzuolo. and Y. Washiztt, 1963: J. Neurophvsiol. 26, 948–957.Google Scholar
  2. Giacobini, E., 1963 a: Science 140,74–75.Google Scholar
  3. Giacobini, E., 1963 b: Abstr. IX Physiol. Congr. Copenhagen. 59. Acta Physiol, Scand., Suppl. 213.Google Scholar
  4. Giacobini, E., 1965a: In: Drugs and Enzymes, Vol. 1V (B. B rod i e ed.),Pergamou Press, pp.55–63. 1965 b: (In press.)Google Scholar
  5. Giacobini, E., 1965 c: Annali Istit. Super. Sanità 1, 500 520.Google Scholar
  6. Giacobini, E., 1966: Acta Physiol. Scand. 66, 34–48.CrossRefGoogle Scholar
  7. Giacobini, E., and A. Grass o, 1966: Acta Physiol. Scand. 66, 49–57.CrossRefGoogle Scholar
  8. Giacobini, E., and P. C. Marchisio, 1965: Acta Physiol. Scand. (ln press.)Google Scholar
  9. Giacobini, E., 1966: Acta Physiol. Scant!. 66, 58–66.CrossRefGoogle Scholar
  10. Giacobini, E., and B. Karlsson, 1965: (In press.)Google Scholar
  11. Giacobini, E., E. Handelman n, and P. C. Ter zu of o, 1965: (In press.)Google Scholar
  12. Lowry, O. H., and J. V. Passonneau, Personal communication.Google Scholar
  13. Giacobini, E., F. X. Hasselberger, and D. W. Schultz, 1964: J. Biol. Chem. 239, 18–30.Google Scholar
  14. Maitra, P. K., A. Ghosh, B. Sehoeuer, and B. Chance, 1964: Biochim. Biophys. Acta 88, 112–119.Google Scholar
  15. Toschi, G., and E. Giacobini, 1965: Life Sciences 4, 1831–1834.CrossRefGoogle Scholar
  16. Whittam, R., 1964: Transport and Diffusion in red blood cells. E. Arnold Ltd. ( London ), pp. 141–142.Google Scholar

Copyright information

© Springer-Verlag Wien 1967

Authors and Affiliations

  • Ezio Giacobini
    • 1
  1. 1.Department of PharmacologyKarolinska InstitutetStockholmSweden

Personalised recommendations