The Vagaries of Diffusion

  • Paul S. Agutter
  • Philip L. Taylor
Part of the Molecular Biology Intelligence Unit book series (MBIU)

Abstract

In the first chapter we noted that molecule movements within a compartment are considered irrelevant to transport just as far as they can be attributed to diffusion; and conversely, so far as a molecule’s movements are not due to diffusion, they must be considered part of transport. We offered prima facie reasons for doubting whether cytoplasmic or nucleoplasmic proteins and RNAs could be held to ‘diffuse’ over distances many times greater than molecular dimensions, but our contention rested on an intuitive understanding of that term. The issue is central to the question of how we should properly conceive of nucleocytoplasmic transport, and is highly relevant to other aspects of cell physiology. It bears directly on the interpretation of experimental work and on the direction of some theorizing. Therefore we need to address the notion of ‘diffusion’ in detail.

Keywords

Permeability Migration Anisotropy Polypeptide Polystyrene 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • Paul S. Agutter
    • 1
  • Philip L. Taylor
    • 2
  1. 1.Napier UniversityEdinburghScotland
  2. 2.EdinburghScotland

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