General Introduction

  • Mark M. Kockx
Part of the Medical Intelligence Unit book series (MIU.LANDES)


One of the most generalized diseases in the human race is athero-sclerosis. It is also the principal cause of death in the Western world. It is characterized by the presence of plaques on the luminal aspect of arteries. The plaques are composed of a mixture of lipid laden foam cells, smooth muscle cells, extracellular lipids, proteoglycans, calcium deposits, collagen and elastic fibers. A constant feature is that they always occur in vessels which possess a structure termed “intima” and that they originate and grow within this intima. Even in transposed or transplanted arteries or veins devoid of an intima atherosclerosis only develops after an intima is formed.


Smooth Muscle Cell Elastic Fiber Intimal Hyperplasia Intimal Thickening Internal Elastic Lamina 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1995

Authors and Affiliations

  • Mark M. Kockx
    • 1
  1. 1.Department of PathologyAlgemeen Ziekenhuis MiddelheimAntwerpBelgium

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