Whole Body Amino Acid Studies in Cancer Cachexia
The mechanisms contributing to cancer cachexia involve complex alterations in host metabolism and physiologic function. In general, malnutrition in cancer patients can be viewed as an imbalance between decreased intake and/or absorption of nutrients and increased demand for nutrients from metabolic derangements and from the tumor. Defining metabolic alterations in the patient with cancer is an extensive field of study and abnormalities have been described in lipid, glucose, energy and protein metabolism. Using techniques described in earlier chapters, changes in protein and amino acid metabolism in the cancer patient can be studied at the whole body as well as at the regional level. This chapter will detail whole body amino acid and protein studies in the tumor-bearing patient.
KeywordsTotal Parenteral Nutrition Branch Chain Amino Acid Body Protein Ketogenic Diet Cancer Cachexia
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