The Protective Effects of Preconditioning on Postischemic Contractile Dysfunction

  • Alison C. Cave
Part of the Medical Intelligence Unit book series (MIU.LANDES)


Ischemic preconditioning is an important phenomenon by which significant myocardial protection can be achieved, paradoxically, by first subjecting the heart to an additional, but brief, period of ischemia and reperfusion.1–4 Studies during the past decade have established that ischemic preconditioning can significantly decrease the extent of postischemic contractile dysfunction1 in addition to reducing the extent of tissue necrosis2 and ischemia-3 or reperfusion-induced arrhythmias.4 The purpose of this chapter however, is to discuss primarily the protection observed against postischemic contractile dysfunction.


Ischemic Precondition Contractile Dysfunction Control Heart Ischemic Period Ischaemic Precondition 
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© Springer-Verlag Berlin Heidelberg 1996

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  • Alison C. Cave

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