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The Nuclear Response to cAMP During Spermatogenesis: The Key Role of Transcription Factor CREM

  • Conference paper
Molecular and Cellular Endocrinology of the Testis

Part of the book series: Ernst Schering Research Foundation Workshop ((SCHERING FOUND,volume 1))

Abstract

The regulation of gene expression by specific signal transduction pathways is closely connected to the cell phenotype, and the response elicited by a given transduction pathway will vary according to the cell type. The finding that most of the known nuclear oncogenes encode proteins involved in the regulation of gene expression inspired the concept that the aberrant expression of some key genes could cause cellular transformation or altered proliferation (Lewin 1991). The study, and ultimately the understanding, of these processes will hopefully help us to unravel the profound changes that cause cancer and, by the same token, the physiology of normal growth.

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G. Verhoeven U.-F. Habenicht

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Sassone-Corsi, P. (1994). The Nuclear Response to cAMP During Spermatogenesis: The Key Role of Transcription Factor CREM. In: Verhoeven, G., Habenicht, UF. (eds) Molecular and Cellular Endocrinology of the Testis. Ernst Schering Research Foundation Workshop, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-22189-1_10

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  • DOI: https://doi.org/10.1007/978-3-662-22189-1_10

  • Publisher Name: Springer, Berlin, Heidelberg

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