Hormonal Receptors in the Genital Tract

  • A. Chauchereau
  • A. Mantel
  • K. Delabre
  • M. Misrahi
  • P. Lescop
  • M. Perrot-Applanat
  • H. Loosfelt
  • M. T. Vu Hai
  • N. Ghinea
  • G. Meduri
  • J.-F. Savouret
  • E. Milgrom
Conference paper
Part of the Ernst Schering Research Foundation Workshop book series (SCHERING FOUND, volume 1)

Abstract

Hormonal receptors are rare and fragile molecules. Their study was difficult and often yielded contradictory results until immunological and molecular probes became available. Sex steroid receptor cDNAs were cloned in 1986–1987. Monoclonal antibodies had previously been prepared and for this reason the understanding of their structure and function is already very advanced to date. In contrast, gonadotropin receptors were not cloned until 1989–1990 and well-characterized antibodies still remain a problem in many cases and thus our knowledge of their mere basic structural and functional features is still preliminary in many cases.

Keywords

Estrogen Dopamine Acid Numbering Serine Oligomerization 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1994

Authors and Affiliations

  • A. Chauchereau
  • A. Mantel
  • K. Delabre
  • M. Misrahi
  • P. Lescop
  • M. Perrot-Applanat
  • H. Loosfelt
  • M. T. Vu Hai
  • N. Ghinea
  • G. Meduri
  • J.-F. Savouret
  • E. Milgrom

There are no affiliations available

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