Perkutane Strahlenbehandlung zur Prophylaxe der frühen Restenose nach Gefäßdilatation und/oder Stent

  • Peter Fritz

Zusammenfassung

Weltweit werden pro Jahr ca. 300000 transluminale Angioplastien durchgeführt. Die prompte Wiedereröffnung des Gefäßes ist allerdings häufig nur von kurzer Dauer. Nach wenigen Monaten treten bei ca. 12–48% aller Patienten Restenosen des dilatierten Gefäßabschnittes auf [4, 5, 8]. Ursache für die frühe Restenose ist die sogenannte „Intimahyperplasie“ [2], welche als überschießender Reparaturversuch der aufgesprengten Gefäßwand anzusehen ist. Diese reparative Hyperproliferation des myofibroblastozytären Apparates findet gleichermaßen auch nach Stentimplantation und operativen Rekonstruktionen statt [11, 14–16, 26].

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© Springer-Verlag Berlin Heidelberg 2000

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  • Peter Fritz

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