Cancer of the Urinary and Reproductive Tracts
An association of ovarian cancer with ABO blood groups has been described in large population samples.1 This was confirmed in a recent study of 1261 women with ovarian cancer. Comparison of blood group A patients with a large normal cohort confirmed earlier findings which stated that the cancer risk in the former group was 1.2 with 1 considered as the risk factor in normals.2 A possible explanation is that many tumors which may express Forssman A-like antigen could be eliminated by naturally occurring anti-A in non-A persons; this form of immune surveillance would be absent in A individuals.
KeywordsOvarian Cancer Blood Group Endometrial Adenocarcinoma BeWo Cell Lewis Antigen
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