Progression of Medullary Thyroid Carcinoma

  • Barry D. Nelkin
Part of the Medical Intelligence Unit book series (MIU.LANDES)

Abstract

Auniversal aspect of cancer development is its multistage nature. Precancerous stages evolve to more advanced stages of malignancy and metastasis. This has been reviewed extensively by Foulds.1,2 Based on observations of karyotypic progression in hematopoietic and other neoplasms, Nowell3 proposed a clonal evolution model for tumor progression. In this model, variant cell clones which possess some growth advantage overgrow the other cells in the tumor.

Keywords

Estrogen Adenosine Oncol Polypeptide Glucocorticoid 

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© Springer-Verlag Berlin Heidelberg 1996

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  • Barry D. Nelkin

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