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Clinical Manifestations of Multiple Endocrine Neoplasia Type 2

  • Douglas W. Ball
Part of the Medical Intelligence Unit book series (MIU.LANDES)

Abstract

Though uncommon in the general population, the multiple endocrine Neoplasia type 2 (MEN 2) syndromes are noteworthy for their distinctive genetic, developmental and biochemical features, and their unique clinical associations. Elucidation of the genetic basis of the MEN 2 syndromes has spawned substantial improvements in diagnosis which in turn have led to more prompt and appropriate treatment of the associated endocrine tumors. In the foreseeable future, greater understanding of the molecular pathogenesis of these tumors is likely to allow a more rational targeting of anti-tumor therapy. This introductory chapter reviews the natural history and summarizes current approaches to diagnosis and management of patients with the MEN 2 syndromes.

Keywords

Medullary Thyroid Carcinoma Multiple Endocrine Neoplasia Type Cutaneous Lichen Amyloidosis Familial Pheochromocytoma Apparent Family History 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 1996

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  • Douglas W. Ball

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