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Clinical Manifestations of Multiple Endocrine Neoplasia Type 2

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Genetic Mechanisms in Multiple Endocrine Neoplasia Type 2

Part of the book series: Medical Intelligence Unit ((MIU.LANDES))

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Abstract

Though uncommon in the general population, the multiple endocrine Neoplasia type 2 (MEN 2) syndromes are noteworthy for their distinctive genetic, developmental and biochemical features, and their unique clinical associations. Elucidation of the genetic basis of the MEN 2 syndromes has spawned substantial improvements in diagnosis which in turn have led to more prompt and appropriate treatment of the associated endocrine tumors. In the foreseeable future, greater understanding of the molecular pathogenesis of these tumors is likely to allow a more rational targeting of anti-tumor therapy. This introductory chapter reviews the natural history and summarizes current approaches to diagnosis and management of patients with the MEN 2 syndromes.

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© 1996 Springer-Verlag Berlin Heidelberg

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Ball, D.W. (1996). Clinical Manifestations of Multiple Endocrine Neoplasia Type 2. In: Genetic Mechanisms in Multiple Endocrine Neoplasia Type 2. Medical Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-21948-5_1

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  • DOI: https://doi.org/10.1007/978-3-662-21948-5_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-21950-8

  • Online ISBN: 978-3-662-21948-5

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