Gap Junctions in the Nervous System: An Introduction

  • David C. Spray
  • Rolf Dermietzel
Part of the Neuroscience Intelligence Unit book series (NIU.LANDES)

Abstract

Acentury ago, it was generally believed that consciousness and movement resulted from the flow of substances freely throughout the interconnected neural network. This Reticular Theory eventually gave way to the Neuronal Doctrine in which the nervous system was envisioned as a composite of discrete cells, where direct transfer of information among neurons is a rare event, occurring only in specialized nuclei and under specific circumstances. Nevertheless, as chapters in this volume testify, gap junctions, the structural elements responsible for direct intercellular communication, are increasingly detected between cells in both the central and peripheral nervous systems of mammals, including man.

Keywords

Permeability Toxicity Recombination Cysteine Carboxyl 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • David C. Spray
  • Rolf Dermietzel

There are no affiliations available

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