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Frontalhirn pp 207-240 | Cite as

Affektive Störungen

  • F. Schneider
  • U. Habel
  • S. Bestmann

Zusammenfassung

Die Pathophysiologie affektiver Störungen ist durch ein ungünstiges Zusammenwirken von früheren und aktuellen Lebensstressoren sowie von genetischen Faktoren bestimmt (Risch 1997). Die Entstehung und der Verlauf affektiver Erkrankungen wird dabei durch komplexe neuromodulatorische Prozesse geregelt, wobei besonders frontostriatalen Regelkreisen eine wichtige Funktion zukommt. Läsionsstudien und Befunde aus bildgebenden Verfahren sowie aus neuropsychologischen Untersuchungen deuten darauf hin, dass morphologische und funktionelle Veränderungen des Präfrontalkortex entscheidend zur Symptomatik beitragen und möglicherweise eines von mehreren determinierenden zerebralen Korrelaten affektiver Störungen darstellt.

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© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • F. Schneider
  • U. Habel
  • S. Bestmann

There are no affiliations available

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