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Mechanisms of Carcinogenesis

  • Lutz Gissmann
  • Günter Krämmer
  • Rudolf Süss
  • Margarete Malter

Abstract

The research focused on “mechanisms of carcinogenesis” is concerned with the fundamental question as to how and why cancer arises. The research projects grouped together here thus have a common concept. Despite all diversity of the experimental approaches, this concept can be described as follows: Model reconstruction of the transformation of a normal cell into a cancer cell under deliberately chosen conditions which allow as complete as possible an observation of the molecular processes leading to cancer development. Experimentation with cancer-inducing rays, chemical carcinogens as well as tumor viruses are in principle equivalent. It is indeed appropriate to experiment with different agents, since cancer is not caused by a single factor but by many causes, and this must be borne in mind in experimentation.

Keywords

Cervical Cancer Human Papilloma Virus Kupffer Cell Cervical Carcinoma Circulate Tumor Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Selected publications

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • Lutz Gissmann
    • 1
  • Günter Krämmer
    • 2
  • Rudolf Süss
    • 3
  • Margarete Malter
    • 3
  1. 1.Genome Modifications and CarcinogenesisInstitute of Virus ResearchGermany
  2. 2.Molecular Biology of the Cell IInstitute of Cell and Tumor BiologyGermany
  3. 3.Project Group Cancer EncyclopediaInstitute of Experimental PathologyGermany

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