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Localization of EF-Hand Ca2+-Binding Proteins in the CNS

  • Chapter
Calcium Regulation by Calcium-Binding Proteins in Neurodegenerative Disorders

Part of the book series: Neuroscience Intelligence Unit ((NIU.LANDES))

Abstract

The intention of this chapter is not to provide a complete review of all the anatomical literature dealing with the distribution of Ca2+-binding proteins in the central nervous system, rather an attempt is made to survey the distribution and cellular localization of Ca2+-binding proteins in selected brain systems of the mammalian brain. Special emphasis is placed on brain systems that are affected in certain neurodegenerative diseases of the human brain, such as hippocampus, cerebellum, basal ganglia and cortical areas. Since, for most of these brain regions, excellent, extensive, and very detailed descriptions of cell types, their distribution and pathways containing different Ca2+-binding proteins have already been published (for reviews see refs. 1–6), the following description is restricted to brain areas and their neurons and functional pathways, which are related to the pathology of brain diseases.

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Authors and Affiliations

  1. University of Zurich, Zurich, Switzerland

    Claus W. Heizmann Ph.D.

  2. Federal Institute for Neurobiology, Magdeburg, Germany

    Katharina Braun Ph.D.

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  1. Claus W. Heizmann Ph.D.
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© 1995 Springer-Verlag Berlin Heidelberg

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Heizmann, C.W., Braun, K. (1995). Localization of EF-Hand Ca2+-Binding Proteins in the CNS. In: Calcium Regulation by Calcium-Binding Proteins in Neurodegenerative Disorders. Neuroscience Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-21689-7_4

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  • DOI: https://doi.org/10.1007/978-3-662-21689-7_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-21691-0

  • Online ISBN: 978-3-662-21689-7

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