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Modulation of Neutrophil Function in Sepsis

  • W. Karzai
  • K. Reinhart
Conference paper
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 2000)

Abstract

The neutrophil plays a crucial role in host defense against microbial infections. Reductions in neutrophil numbers predispose the inflicted individuals to recurring and life-threatening bouts of infectious disease. In patients undergoing chemotherapy or in patients suffering from cyclic neutropenia, the incidence and prevalence of infections decrease with increasing numbers of neutrophils [1–3]. Furthermore, functional abnormalities of neutrophils such as deficiency of respiratory burst also lead to recurrent serious infections despite normal neutrophil counts [4].

Keywords

Neutrophil Function Neutrophil Number Cyclic Neutropenia Chronic Neutropenia Increase Neutrophil Count 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • W. Karzai
  • K. Reinhart

There are no affiliations available

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