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Anabolic Strategy in ICU Patients: Is there a Place for Growth Hormone?

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine 1999

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 1999))

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Abstract

Critically ill patients undergo prolonged severe metabolic stress and immobilization with major muscle wasting, as reflected by a negative nitrogen balance [1]. In addition to muscle mass catabolism, major muscle dysfunction, such as prolonged relaxation rate, decrease maximal force and increased fatigability, is observed [2]. These alterations are characteristic of protein calorie malnutrition which is associated with immune dysfunction and increased risk of infection, in turn responsible for the initiation of a vicious circle ultimately promoting further catabolism. Such a state of protein calorie malnutrition is often correlated to increased morbidity, prolonged periods of mechanical ventilatory assistance, length of stay and duration of rehabilitation [3].

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Authors
  1. C. Pichard
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  2. P. Jolliet
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  3. J.-A. Romand
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Clinical Director) (Clinical Director)

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© 1999 Springer-Verlag Berlin Heidelberg

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Pichard, C., Jolliet, P., Romand, JA. (1999). Anabolic Strategy in ICU Patients: Is there a Place for Growth Hormone?. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 1999. Yearbook of Intensive Care and Emergency Medicine, vol 1999. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-13453-5_9

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  • DOI: https://doi.org/10.1007/978-3-662-13453-5_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-65288-5

  • Online ISBN: 978-3-662-13453-5

  • eBook Packages: Springer Book Archive

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