Abstract
Controlled mechanical ventilation with/without positive end-expiratory pressure (PEEP) helps in many cases to overcome life-threatening respiratory failure. However, it has some important shortcomings which may lead to potentially deleterious side effects due to substantial differences between mechanical ventilation and spontaneous breathing. During spontaneous breathing, mean transpulmonary pressure is situated around atmospheric pressure whereas pleural pressure is always subatmospheric. Ventilatory pattern varies and tidal volumes are around 7 mL/kg BW. Inspiration is due to an active, dorsal enhanced contraction of the diaphragm and airway resistance is low and mainly situated in the area of the upper airways [1].
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Stocker, R., Fabry, B., Haberthür, C. (1997). New Modes of Ventilatory Support in Spontaneously Breathing Intubated Patients. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 1997. Yearbook of Intensive Care and Emergency Medicine, vol 1997. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-13450-4_43
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DOI: https://doi.org/10.1007/978-3-662-13450-4_43
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