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Activation of Poly-(ADP-Ribose) Synthetase by Peroxynitrite

  • Conference paper
Yearbook of Intensive Care and Emergency Medicine 1997

Part of the book series: Yearbook of Intensive Care and Emergency Medicine ((YEARBOOK,volume 1997))

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Abstract

Over the last several decades, there has been a substantial body of work implicating the pathophysiological roles of oxygen-derived free radicals in various forms of circulatory shock [1, 2]. More recently, it became also evident that the free radical nitric oxide (NO) serves a number of physiological and pathophysiological functions in the body, wherein the expression of the inducible isoform of NO synthase (NOS) has been proposed as an important mediator of the cardiovascular failure in shock [3, 4].

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Authors
  1. C. Szabó
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Clinical Director) (Clinical Director)

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© 1997 Springer-Verlag Berlin Heidelberg

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Szabó, C. (1997). Activation of Poly-(ADP-Ribose) Synthetase by Peroxynitrite. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 1997. Yearbook of Intensive Care and Emergency Medicine, vol 1997. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-13450-4_21

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  • DOI: https://doi.org/10.1007/978-3-662-13450-4_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-13452-8

  • Online ISBN: 978-3-662-13450-4

  • eBook Packages: Springer Book Archive

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